Tetrahedron

, volume 75 , issue 7 , pages 874-887

Total synthesis of carbazole alkaloids

BHARATH KUMAR GOUD BHATTHULA ¹

Janardhan Reddy Kanchani ²

Veera Reddy Arava ¹

M. C. S. Subha ³

Hide authors affiliations Show authors affiliations: 3 affiliations

Research and Development Center, Suven Life Sciences Limited., Hyderabad, India |

Department of Chemistry, Sri Krishnadevaraya University, Anantapur, India |

Publication type: Journal Article

Publication date: 2019-02-01

Elsevier

Tetrahedron

scimago Q3

wos Q2

SJR: 0.426

CiteScore: 4.1

Impact factor: 2.2

ISSN: 00404020, 14645416

DOI: 10.1016/j.tet.2019.01.003

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Organic Chemistry

Drug Discovery

Biochemistry

Abstract

A Suzuki-Miyaura cross coupling, followed by triphenylphosphine mediated Cadogan reductive cyclization sequence provided efficient access to a series of carbazole alkaloids. In the present work, this approach was applied to the total synthesis of mukonine, clauszoline K, koenoline, murrayanine, murrayafoline A, mukoeic acid, glycoborine, glycozolicine, mukolidine, mukoline, glycozoline, 3-methoxy-9H-carbazole-1-carboxylic acid methyl ester, (3-methoxy-9H-carbazol-1-yl)-methanol, 3-methoxy-9H-carbazole-1-carbaldehyde, 3-methoxy-9H-carbazole-1-carboxylic acid, 2-methyl-9H-carbazole and nonsteroidal anti-inflammatory drug (NSAID) carprofen and its derivatives.

Found

1 citation

Lvov Andrey

DSc in Chemistry

79 publications, 1 123 citations, 32 reviews

h-index: 20

A.E. Favorsky Irkutsk Institute of Chemistry of the Siberian Branch of the Russian Academy of Sciences

Irkutsk National Research Technical University

Research interests

Heterocyclic compounds

Organic Chemistry

Photochemistry

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GOST |

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GOST Copy

BHATTHULA B. K. G. et al. Total synthesis of carbazole alkaloids // Tetrahedron. 2019. Vol. 75. No. 7. pp. 874-887.

GOST all authors (up to 50) Copy

BHATTHULA B. K. G., Kanchani J. R., Arava V. R., Subha M. C. S. Total synthesis of carbazole alkaloids // Tetrahedron. 2019. Vol. 75. No. 7. pp. 874-887.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1016/j.tet.2019.01.003

UR - https://doi.org/10.1016/j.tet.2019.01.003

TI - Total synthesis of carbazole alkaloids

T2 - Tetrahedron

AU - BHATTHULA, BHARATH KUMAR GOUD

AU - Kanchani, Janardhan Reddy

AU - Arava, Veera Reddy

AU - Subha, M. C. S.

PY - 2019

DA - 2019/02/01

PB - Elsevier

SP - 874-887

IS - 7

VL - 75

SN - 0040-4020

SN - 1464-5416

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2019_BHATTHULA,

author = {BHARATH KUMAR GOUD BHATTHULA and Janardhan Reddy Kanchani and Veera Reddy Arava and M. C. S. Subha},

title = {Total synthesis of carbazole alkaloids},

journal = {Tetrahedron},

year = {2019},

volume = {75},

publisher = {Elsevier},

month = {feb},

url = {https://doi.org/10.1016/j.tet.2019.01.003},

number = {7},

pages = {874--887},

doi = {10.1016/j.tet.2019.01.003}

}

MLA

Cite this

MLA Copy

BHATTHULA, BHARATH KUMAR GOUD, et al. “Total synthesis of carbazole alkaloids.” Tetrahedron, vol. 75, no. 7, Feb. 2019, pp. 874-887. https://doi.org/10.1016/j.tet.2019.01.003.

Publisher

Elsevier

Journal

Tetrahedron

scimago Q3

wos Q2

SJR

0.426

CiteScore

4.1

Impact factor

2.2

ISSN

00404020 (Print)

14645416 (Electronic)