Synthesis of substituted carbazoles and β -carbolines by cyclization of diketoindole derivatives
Publication type: Journal Article
Publication date: 2004-07-01
scimago Q3
wos Q3
SJR: 0.334
CiteScore: 3.2
Impact factor: 1.5
ISSN: 00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
A new route to substituted β -carbolines and carbazoles is described. Diketoindole intermediates, prepared by Friedel–Crafts acylations of 3-substituted indoles, have been converted to 3-hydroxycarbazoles and β -carbolines in good yields, 51–96% and 82–97%, respectively. This method also allows for the formation of 4-substituted β -carbolines. The application of this methodology to the synthesis of the natural products hyellazole and 6-chlorohyellazole is also described.
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48
Total citations:
48
Citations from 2024:
5
(10.42%)
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GOST
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Duval E., Cuny G. D. Synthesis of substituted carbazoles and β -carbolines by cyclization of diketoindole derivatives // Tetrahedron Letters. 2004. Vol. 45. No. 28. pp. 5411-5413.
GOST all authors (up to 50)
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Duval E., Cuny G. D. Synthesis of substituted carbazoles and β -carbolines by cyclization of diketoindole derivatives // Tetrahedron Letters. 2004. Vol. 45. No. 28. pp. 5411-5413.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.tetlet.2004.05.053
UR - https://doi.org/10.1016/j.tetlet.2004.05.053
TI - Synthesis of substituted carbazoles and β -carbolines by cyclization of diketoindole derivatives
T2 - Tetrahedron Letters
AU - Duval, Eric
AU - Cuny, Gregory D
PY - 2004
DA - 2004/07/01
PB - Elsevier
SP - 5411-5413
IS - 28
VL - 45
SN - 0040-4039
SN - 1873-3581
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2004_Duval,
author = {Eric Duval and Gregory D Cuny},
title = {Synthesis of substituted carbazoles and β -carbolines by cyclization of diketoindole derivatives},
journal = {Tetrahedron Letters},
year = {2004},
volume = {45},
publisher = {Elsevier},
month = {jul},
url = {https://doi.org/10.1016/j.tetlet.2004.05.053},
number = {28},
pages = {5411--5413},
doi = {10.1016/j.tetlet.2004.05.053}
}
Cite this
MLA
Copy
Duval, Eric, and Gregory D Cuny. “Synthesis of substituted carbazoles and β -carbolines by cyclization of diketoindole derivatives.” Tetrahedron Letters, vol. 45, no. 28, Jul. 2004, pp. 5411-5413. https://doi.org/10.1016/j.tetlet.2004.05.053.