One-pot synthesis of α-alkylated nitriles with carbonyl compounds through consecutive aldol reaction/hydrogenation using a hydrotalcite-supported palladium nanoparticle as a multifunctional heterogeneous catalyst
Ken Motokura
1
,
Noriaki FUJITA
1
,
Kohsuke Mori
1
,
Tomoo Mizugaki
1
,
Kohki Ebitani
1
,
K. Kaneda
1
Publication type: Journal Article
Publication date: 2005-08-01
scimago Q3
wos Q3
SJR: 0.334
CiteScore: 3.2
Impact factor: 1.5
ISSN: 00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
α-Alkylation of various nitriles with carbonyl compounds successfully proceeded using a hydrotalcite-supported palladium nanoparticle as a multifunctional catalyst. The alkylated nitriles were formed through aldol reaction at base sites on the hydrotalcite surface followed by hydrogenation by molecular hydrogen on the palladium nanoparticle.
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57
Total citations:
57
Citations from 2025:
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GOST
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Motokura K. et al. One-pot synthesis of α-alkylated nitriles with carbonyl compounds through consecutive aldol reaction/hydrogenation using a hydrotalcite-supported palladium nanoparticle as a multifunctional heterogeneous catalyst // Tetrahedron Letters. 2005. Vol. 46. No. 33. pp. 5507-5510.
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Motokura K., FUJITA N., Mori K., Mizugaki T., Ebitani K., Kaneda K. One-pot synthesis of α-alkylated nitriles with carbonyl compounds through consecutive aldol reaction/hydrogenation using a hydrotalcite-supported palladium nanoparticle as a multifunctional heterogeneous catalyst // Tetrahedron Letters. 2005. Vol. 46. No. 33. pp. 5507-5510.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.tetlet.2005.06.053
UR - https://doi.org/10.1016/j.tetlet.2005.06.053
TI - One-pot synthesis of α-alkylated nitriles with carbonyl compounds through consecutive aldol reaction/hydrogenation using a hydrotalcite-supported palladium nanoparticle as a multifunctional heterogeneous catalyst
T2 - Tetrahedron Letters
AU - Motokura, Ken
AU - FUJITA, Noriaki
AU - Mori, Kohsuke
AU - Mizugaki, Tomoo
AU - Ebitani, Kohki
AU - Kaneda, K.
PY - 2005
DA - 2005/08/01
PB - Elsevier
SP - 5507-5510
IS - 33
VL - 46
SN - 0040-4039
SN - 1873-3581
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2005_Motokura,
author = {Ken Motokura and Noriaki FUJITA and Kohsuke Mori and Tomoo Mizugaki and Kohki Ebitani and K. Kaneda},
title = {One-pot synthesis of α-alkylated nitriles with carbonyl compounds through consecutive aldol reaction/hydrogenation using a hydrotalcite-supported palladium nanoparticle as a multifunctional heterogeneous catalyst},
journal = {Tetrahedron Letters},
year = {2005},
volume = {46},
publisher = {Elsevier},
month = {aug},
url = {https://doi.org/10.1016/j.tetlet.2005.06.053},
number = {33},
pages = {5507--5510},
doi = {10.1016/j.tetlet.2005.06.053}
}
Cite this
MLA
Copy
Motokura, Ken, et al. “One-pot synthesis of α-alkylated nitriles with carbonyl compounds through consecutive aldol reaction/hydrogenation using a hydrotalcite-supported palladium nanoparticle as a multifunctional heterogeneous catalyst.” Tetrahedron Letters, vol. 46, no. 33, Aug. 2005, pp. 5507-5510. https://doi.org/10.1016/j.tetlet.2005.06.053.