Greener and rapid access to bio-active heterocycles: one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles
1
Sustainable Technology Division, National Risk Management Research Laboratory, US Environmental Protection Agency, 26 West Martin Luther King Drive, MS 443, Cincinnati, OH 45268, USA
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Publication type: Journal Article
Publication date: 2008-01-01
scimago Q3
wos Q3
SJR: 0.334
CiteScore: 3.2
Impact factor: 1.5
ISSN: 00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
A novel one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles by condensation of acid hydrazide and triethyl orthoalkanates under microwave irradiations is reported. This green protocol was catalyzed efficiently by solid supported Nafion®NR50 and phosphorus pentasulfide in alumina (P4S10/Al2O3) with excellent yields.
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111
Total citations:
111
Citations from 2024:
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(8.1%)
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GOST
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Polshettiwar V., Varma R. S. Greener and rapid access to bio-active heterocycles: one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles // Tetrahedron Letters. 2008. Vol. 49. No. 5. pp. 879-883.
GOST all authors (up to 50)
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Polshettiwar V., Varma R. S. Greener and rapid access to bio-active heterocycles: one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles // Tetrahedron Letters. 2008. Vol. 49. No. 5. pp. 879-883.
Cite this
RIS
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TY - JOUR
DO - 10.1016/j.tetlet.2007.11.165
UR - https://doi.org/10.1016/j.tetlet.2007.11.165
TI - Greener and rapid access to bio-active heterocycles: one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles
T2 - Tetrahedron Letters
AU - Polshettiwar, Vivek
AU - Varma, Rajender S.
PY - 2008
DA - 2008/01/01
PB - Elsevier
SP - 879-883
IS - 5
VL - 49
SN - 0040-4039
SN - 1873-3581
ER -
Cite this
BibTex (up to 50 authors)
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@article{2008_Polshettiwar,
author = {Vivek Polshettiwar and Rajender S. Varma},
title = {Greener and rapid access to bio-active heterocycles: one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles},
journal = {Tetrahedron Letters},
year = {2008},
volume = {49},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/j.tetlet.2007.11.165},
number = {5},
pages = {879--883},
doi = {10.1016/j.tetlet.2007.11.165}
}
Cite this
MLA
Copy
Polshettiwar, Vivek, and Rajender S. Varma. “Greener and rapid access to bio-active heterocycles: one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles.” Tetrahedron Letters, vol. 49, no. 5, Jan. 2008, pp. 879-883. https://doi.org/10.1016/j.tetlet.2007.11.165.