volume 52 issue 18 pages 2362-2366

Novel and efficient aqueous phase synthesis of N-substituted azepines via tandem Michael addition and cyclization in the presence of β-cyclodextrin

Publication typeJournal Article
Publication date2011-05-01
scimago Q3
wos Q3
SJR0.334
CiteScore3.2
Impact factor1.5
ISSN00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
N-substituted azepines were synthesized for the first time in water under neutral conditions by the reaction of aromatic amines, dimethyl/diethyl acetylene dicarboxylate, 2,5-dimethoxytetrahydrofuran mediated by β-cyclodextrin in high yields. β-Cyclodextrin can be recovered and reused with just a small loss of catalytic activity.
Found 
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GOST Copy
Ramesh S., Murthy S. N., Nageswar Y. V. D. Novel and efficient aqueous phase synthesis of N-substituted azepines via tandem Michael addition and cyclization in the presence of β-cyclodextrin // Tetrahedron Letters. 2011. Vol. 52. No. 18. pp. 2362-2366.
GOST all authors (up to 50) Copy
Ramesh S., Murthy S. N., Nageswar Y. V. D. Novel and efficient aqueous phase synthesis of N-substituted azepines via tandem Michael addition and cyclization in the presence of β-cyclodextrin // Tetrahedron Letters. 2011. Vol. 52. No. 18. pp. 2362-2366.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.tetlet.2011.02.082
UR - https://doi.org/10.1016/j.tetlet.2011.02.082
TI - Novel and efficient aqueous phase synthesis of N-substituted azepines via tandem Michael addition and cyclization in the presence of β-cyclodextrin
T2 - Tetrahedron Letters
AU - Ramesh, Subramaniam
AU - Murthy, S Narayana
AU - Nageswar, Y. V. D.
PY - 2011
DA - 2011/05/01
PB - Elsevier
SP - 2362-2366
IS - 18
VL - 52
SN - 0040-4039
SN - 1873-3581
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2011_Ramesh,
author = {Subramaniam Ramesh and S Narayana Murthy and Y. V. D. Nageswar},
title = {Novel and efficient aqueous phase synthesis of N-substituted azepines via tandem Michael addition and cyclization in the presence of β-cyclodextrin},
journal = {Tetrahedron Letters},
year = {2011},
volume = {52},
publisher = {Elsevier},
month = {may},
url = {https://doi.org/10.1016/j.tetlet.2011.02.082},
number = {18},
pages = {2362--2366},
doi = {10.1016/j.tetlet.2011.02.082}
}
MLA
Cite this
MLA Copy
Ramesh, Subramaniam, et al. “Novel and efficient aqueous phase synthesis of N-substituted azepines via tandem Michael addition and cyclization in the presence of β-cyclodextrin.” Tetrahedron Letters, vol. 52, no. 18, May. 2011, pp. 2362-2366. https://doi.org/10.1016/j.tetlet.2011.02.082.