One-pot synthesis of carbazoles from indoles via a metal free benzannulation
Publication type: Journal Article
Publication date: 2017-11-01
scimago Q3
wos Q3
SJR: 0.334
CiteScore: 3.2
Impact factor: 1.5
ISSN: 00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
We report a simple, one-pot, and metal free benzannulation protocol to carbazoles starting with indoles, carbonyl compounds and an appropriate dienophiles. Mechanistically, this strategy generates an in situ diene by condensation between indole and carbonyl compound succeed and subsequent dehydration. Later, Diels–Alder reaction of this diene with a suitable dienophile followed by oxidation delivers the carbazole derivative. This methodology provide an easy access to carbazoles containing 1,4-naphthoquinone moiety.
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Total citations:
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Citations from 2024:
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(18.18%)
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GOST
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Kotha S., Aswar V. R., Chinnam A. K. One-pot synthesis of carbazoles from indoles via a metal free benzannulation // Tetrahedron Letters. 2017. Vol. 58. No. 46. pp. 4360-4362.
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Kotha S., Aswar V. R., Chinnam A. K. One-pot synthesis of carbazoles from indoles via a metal free benzannulation // Tetrahedron Letters. 2017. Vol. 58. No. 46. pp. 4360-4362.
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RIS
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TY - JOUR
DO - 10.1016/j.tetlet.2017.10.002
UR - https://doi.org/10.1016/j.tetlet.2017.10.002
TI - One-pot synthesis of carbazoles from indoles via a metal free benzannulation
T2 - Tetrahedron Letters
AU - Kotha, Sambasivarao
AU - Aswar, Vikas R
AU - Chinnam, Ajay Kumar
PY - 2017
DA - 2017/11/01
PB - Elsevier
SP - 4360-4362
IS - 46
VL - 58
SN - 0040-4039
SN - 1873-3581
ER -
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BibTex (up to 50 authors)
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@article{2017_Kotha,
author = {Sambasivarao Kotha and Vikas R Aswar and Ajay Kumar Chinnam},
title = {One-pot synthesis of carbazoles from indoles via a metal free benzannulation},
journal = {Tetrahedron Letters},
year = {2017},
volume = {58},
publisher = {Elsevier},
month = {nov},
url = {https://doi.org/10.1016/j.tetlet.2017.10.002},
number = {46},
pages = {4360--4362},
doi = {10.1016/j.tetlet.2017.10.002}
}
Cite this
MLA
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Kotha, Sambasivarao, et al. “One-pot synthesis of carbazoles from indoles via a metal free benzannulation.” Tetrahedron Letters, vol. 58, no. 46, Nov. 2017, pp. 4360-4362. https://doi.org/10.1016/j.tetlet.2017.10.002.