Ethyl 5-trichloromethyl-1,2,4-oxadiazole-3-carboxylate as a versatile building block in medicinal chemistry
Publication type: Journal Article
Publication date: 2018-12-01
scimago Q3
wos Q3
SJR: 0.334
CiteScore: 3.2
Impact factor: 1.5
ISSN: 00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
A straightforward route for preparing derivatives of ethyl 5-trichloromethyl-1,2,4-oxadiazole-3-carboxylate, in which the 5-trichloromethyl and/or the ester functionalities are displaced by various nucleophiles, has been designed. Mild reaction conditions were chosen to enable the formation of products, which constitute a new series of bifunctional 3,5-disubstituted 1,2,4-oxadiazole building blocks capable of being integrated into biologically relevant molecules.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
|
|
|
Organic and Biomolecular Chemistry
2 publications, 25%
|
|
|
Tetrahedron Letters
1 publication, 12.5%
|
|
|
ChemistrySelect
1 publication, 12.5%
|
|
|
Journal of Heterocyclic Chemistry
1 publication, 12.5%
|
|
|
Advanced Synthesis and Catalysis
1 publication, 12.5%
|
|
|
Synthesis
1 publication, 12.5%
|
|
|
1
2
|
Publishers
|
1
2
3
|
|
|
Wiley
3 publications, 37.5%
|
|
|
Royal Society of Chemistry (RSC)
2 publications, 25%
|
|
|
Elsevier
1 publication, 12.5%
|
|
|
Georg Thieme Verlag KG
1 publication, 12.5%
|
|
|
1
2
3
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
9
Total citations:
9
Citations from 2024:
1
(12.5%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Jakopin Ž. Ethyl 5-trichloromethyl-1,2,4-oxadiazole-3-carboxylate as a versatile building block in medicinal chemistry // Tetrahedron Letters. 2018. Vol. 59. No. 49. pp. 4320-4322.
GOST all authors (up to 50)
Copy
Jakopin Ž. Ethyl 5-trichloromethyl-1,2,4-oxadiazole-3-carboxylate as a versatile building block in medicinal chemistry // Tetrahedron Letters. 2018. Vol. 59. No. 49. pp. 4320-4322.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.tetlet.2018.10.054
UR - https://doi.org/10.1016/j.tetlet.2018.10.054
TI - Ethyl 5-trichloromethyl-1,2,4-oxadiazole-3-carboxylate as a versatile building block in medicinal chemistry
T2 - Tetrahedron Letters
AU - Jakopin, Žiga
PY - 2018
DA - 2018/12/01
PB - Elsevier
SP - 4320-4322
IS - 49
VL - 59
SN - 0040-4039
SN - 1873-3581
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2018_Jakopin,
author = {Žiga Jakopin},
title = {Ethyl 5-trichloromethyl-1,2,4-oxadiazole-3-carboxylate as a versatile building block in medicinal chemistry},
journal = {Tetrahedron Letters},
year = {2018},
volume = {59},
publisher = {Elsevier},
month = {dec},
url = {https://doi.org/10.1016/j.tetlet.2018.10.054},
number = {49},
pages = {4320--4322},
doi = {10.1016/j.tetlet.2018.10.054}
}
Cite this
MLA
Copy
Jakopin, Žiga, et al. “Ethyl 5-trichloromethyl-1,2,4-oxadiazole-3-carboxylate as a versatile building block in medicinal chemistry.” Tetrahedron Letters, vol. 59, no. 49, Dec. 2018, pp. 4320-4322. https://doi.org/10.1016/j.tetlet.2018.10.054.