TrAC - Trends in Analytical Chemistry, volume 157, pages 116738

Aptamer-based biosensors for virus protein detection

Beibei Lou
Yanfei Liu
Meilin Shi
Jun Chen
Ke Li
Yifu Tan
Li-Wei Chen
Yuwei Wu
Ting Wang
Xiao Qin Liu
Ting Ting Jiang
Dongming Peng
Zhenbao Liu
Publication typeJournal Article
Publication date2022-12-01
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor13.1
ISSN01659936
Spectroscopy
Analytical Chemistry
Abstract
Virus threatens life health seriously. The accurate early diagnosis of the virus is vital for clinical control and treatment of virus infection. Aptamers are small single-stranded oligonucleotides (DNAs or RNAs). In this review, we summarized aptasensors for virus detection in recent years according to the classification of the viral target protein, and illustrated common detection mechanisms in the aptasensors (colorimetry, fluorescence assay, surface plasmon resonance (SPR), surface-enhanced raman spectroscopy (SERS), electrochemical detection, and field-effect transistor (FET)). Furthermore, aptamers against different target proteins of viruses were summarized. The relationships between the different biomarkers of the viruses and the detection methods, and their performances were revealed. In addition, the challenges and future directions of aptasensors were discussed. This review will provide valuable references for constructing on-site aptasensors for detecting viruses, especially the SARS-CoV-2.

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GOST Copy
Lou B. et al. Aptamer-based biosensors for virus protein detection // TrAC - Trends in Analytical Chemistry. 2022. Vol. 157. p. 116738.
GOST all authors (up to 50) Copy
Lou B., Liu Y., Shi M., Chen J., Li K., Tan Y., Chen L., Wu Y., Wang T., Liu X. Q., Jiang T. T., Peng D., Liu Z. Aptamer-based biosensors for virus protein detection // TrAC - Trends in Analytical Chemistry. 2022. Vol. 157. p. 116738.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/j.trac.2022.116738
UR - https://doi.org/10.1016/j.trac.2022.116738
TI - Aptamer-based biosensors for virus protein detection
T2 - TrAC - Trends in Analytical Chemistry
AU - Lou, Beibei
AU - Liu, Yanfei
AU - Shi, Meilin
AU - Chen, Jun
AU - Li, Ke
AU - Tan, Yifu
AU - Chen, Li-Wei
AU - Wu, Yuwei
AU - Wang, Ting
AU - Liu, Xiao Qin
AU - Jiang, Ting Ting
AU - Peng, Dongming
AU - Liu, Zhenbao
PY - 2022
DA - 2022/12/01 00:00:00
PB - Elsevier
SP - 116738
VL - 157
SN - 0165-9936
ER -
BibTex
Cite this
BibTex Copy
@article{2022_Lou,
author = {Beibei Lou and Yanfei Liu and Meilin Shi and Jun Chen and Ke Li and Yifu Tan and Li-Wei Chen and Yuwei Wu and Ting Wang and Xiao Qin Liu and Ting Ting Jiang and Dongming Peng and Zhenbao Liu},
title = {Aptamer-based biosensors for virus protein detection},
journal = {TrAC - Trends in Analytical Chemistry},
year = {2022},
volume = {157},
publisher = {Elsevier},
month = {dec},
url = {https://doi.org/10.1016/j.trac.2022.116738},
pages = {116738},
doi = {10.1016/j.trac.2022.116738}
}
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