The synthesis and cytotoxicity of fructose-1-SNAP, a novel fructose conjugated S-nitroso nitric oxide donor
Тип публикации: Journal Article
Дата публикации: 2001-01-01
scimago Q3
wos Q3
БС2
SJR: 0.334
CiteScore: 3.2
Impact factor: 1.5
ISSN: 00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Краткое описание
An efficient synthetic strategy has been developed for the synthesis of a novel fructose conjugated S-nitroso nitric oxide donor, fructose-1-S-nitroso-N-acetylpenicillamine. This compound showed similar cytotoxicity as the first generation fructose-SNAP, fructose-2-SNAP. A 5- and 26-fold increased cytotoxicity was observed compared to glucose-2-SNAP and SNAP against DU-145 human prostate cancer cells in vitro.
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ГОСТ
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Hou Y. et al. The synthesis and cytotoxicity of fructose-1-SNAP, a novel fructose conjugated S-nitroso nitric oxide donor // Tetrahedron Letters. 2001. Vol. 42. No. 5. pp. 825-829.
ГОСТ со всеми авторами (до 50)
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Hou Y., Wu X., Xie W., Braunschweiger P. G., Wang P. The synthesis and cytotoxicity of fructose-1-SNAP, a novel fructose conjugated S-nitroso nitric oxide donor // Tetrahedron Letters. 2001. Vol. 42. No. 5. pp. 825-829.
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TY - JOUR
DO - 10.1016/s0040-4039(00)02158-4
UR - https://doi.org/10.1016/s0040-4039(00)02158-4
TI - The synthesis and cytotoxicity of fructose-1-SNAP, a novel fructose conjugated S-nitroso nitric oxide donor
T2 - Tetrahedron Letters
AU - Hou, Yongchun
AU - Wu, Xuejun
AU - Xie, Wenhua
AU - Braunschweiger, Paul G
AU - Wang, Peng
PY - 2001
DA - 2001/01/01
PB - Elsevier
SP - 825-829
IS - 5
VL - 42
SN - 0040-4039
SN - 1873-3581
ER -
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BibTex (до 50 авторов)
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@article{2001_Hou,
author = {Yongchun Hou and Xuejun Wu and Wenhua Xie and Paul G Braunschweiger and Peng Wang},
title = {The synthesis and cytotoxicity of fructose-1-SNAP, a novel fructose conjugated S-nitroso nitric oxide donor},
journal = {Tetrahedron Letters},
year = {2001},
volume = {42},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/s0040-4039(00)02158-4},
number = {5},
pages = {825--829},
doi = {10.1016/s0040-4039(00)02158-4}
}
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MLA
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Hou, Yongchun, et al. “The synthesis and cytotoxicity of fructose-1-SNAP, a novel fructose conjugated S-nitroso nitric oxide donor.” Tetrahedron Letters, vol. 42, no. 5, Jan. 2001, pp. 825-829. https://doi.org/10.1016/s0040-4039(00)02158-4.