American Chemical Society (ACS)
Journal of Organic Chemistry
,  volume 85 ,  issue 19 ,  pages 12128-12146

Synthesis of 2-(1H-Indol-2-yl)acetamides via Bronsted Acid-Assisted Cyclization Cascade.

Publication type: Journal Article
Publication date: 2020-09-03
American Chemical Society (ACS)
scimago Q2
wos Q1
SJR: 0.737
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
Organic Chemistry
Abstract
Efficient and straightforward Bronsted-acid mediated cascade process was developed, involving cyclization of readily available beta-ketonitriles into 2-aminofurans and their subsequent recyclization into 2-(1H-indol-2-yl)acetamides is developed. This synthetic route opens a new avenue for an expeditious assembly of various isotryptamine derivatives for medicinal chemistry.
Found 
Found 
9 citations
Aksenov Aleksandr
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DSc in Chemistry, professor
243 publications,  2 187 citations,  15 reviews
h-index: 24
North Caucasus Federal University
North Caucasus Federal University
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Medicinal Chemistry
Organic Chemistry
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Kurenkov Igor
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North Caucasus Federal University
North Caucasus Federal University
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Sosnovskikh Vyacheslav
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Ural Federal University
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Fershtat Leonid
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N.D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences
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Borshchev Oleg
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Enikolopov Institute of Synthetic Polymeric Materials of the Russian Academy of Sciences
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A.N.Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences
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Gazizov Almir
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A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
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North Caucasus Federal University
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Zagidullin Almaz
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Ivleva Elena
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Samara State Technical University
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N.D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences
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Mendeleev University of Chemical Technology of Russia
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A.E. Favorsky Irkutsk Institute of Chemistry of the Siberian Branch of the Russian Academy of Sciences
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GOST Copy
Aksenov N. A. et al. Synthesis of 2-(1H-Indol-2-yl)acetamides via Bronsted Acid-Assisted Cyclization Cascade. // Journal of Organic Chemistry. 2020. Vol. 85. No. 19. pp. 12128-12146.
GOST all authors (up to 50) Copy
Aksenov N. A., Aksenov D. A., Skomorokhov A. A., Prityko L. A., Aksenov A., Griaznov G. D., Rubin M. Synthesis of 2-(1H-Indol-2-yl)acetamides via Bronsted Acid-Assisted Cyclization Cascade. // Journal of Organic Chemistry. 2020. Vol. 85. No. 19. pp. 12128-12146.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/acs.joc.0c01344
UR - https://doi.org/10.1021/acs.joc.0c01344
TI - Synthesis of 2-(1H-Indol-2-yl)acetamides via Bronsted Acid-Assisted Cyclization Cascade.
T2 - Journal of Organic Chemistry
AU - Aksenov, Nicolai A.
AU - Aksenov, Dmitrii A
AU - Skomorokhov, Anton A
AU - Prityko, Lidiya A
AU - Aksenov, Alexander V.
AU - Griaznov, Georgii D
AU - Rubin, Michael
PY - 2020
DA - 2020/09/03
PB - American Chemical Society (ACS)
SP - 12128-12146
IS - 19
VL - 85
PMID - 32881523
SN - 0022-3263
SN - 1520-6904
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2020_Aksenov,
author = {Nicolai A. Aksenov and Dmitrii A Aksenov and Anton A Skomorokhov and Lidiya A Prityko and Alexander V. Aksenov and Georgii D Griaznov and Michael Rubin},
title = {Synthesis of 2-(1H-Indol-2-yl)acetamides via Bronsted Acid-Assisted Cyclization Cascade.},
journal = {Journal of Organic Chemistry},
year = {2020},
volume = {85},
publisher = {American Chemical Society (ACS)},
month = {sep},
url = {https://doi.org/10.1021/acs.joc.0c01344},
number = {19},
pages = {12128--12146},
doi = {10.1021/acs.joc.0c01344}
}
MLA
Cite this
MLA Copy
Aksenov, Nicolai A., et al. “Synthesis of 2-(1H-Indol-2-yl)acetamides via Bronsted Acid-Assisted Cyclization Cascade..” Journal of Organic Chemistry, vol. 85, no. 19, Sep. 2020, pp. 12128-12146. https://doi.org/10.1021/acs.joc.0c01344.