Reductive Cleavage of 4′H-Spiro[indole-3,5′-isoxazoles] En Route to 2-(1H-Indol-3-yl)acetamides with Anticancer Activities
Nikita K Kirilov
1
,
Dmitrii A Aksenov
1
,
Iliya K Kuzminov
1
,
Danielle N Turner
2
,
Snezna Rogelj
2
,
Alexander Kornienko
3
,
Michael Rubin
1, 4
Publication type: Journal Article
Publication date: 2022-10-19
scimago Q2
wos Q1
SJR: 0.737
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
PubMed ID:
36260110
Organic Chemistry
Abstract
Unusual cascade transformation involving ring opening and 1,2-alkyl shift was observed upon the reduction of 4'H-spiro[indole-3,5'-isoxazoles] or 2-(3-oxoindolin-2-yl)acetonitriles with sodium borohydride. This reaction allowed for expeditious and highly efficient preparation of 2-(1H-Indol-3-yl)acetamides with antiproliferative properties.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
|
|
|
Molecules
3 publications, 20%
|
|
|
Tetrahedron Letters
1 publication, 6.67%
|
|
|
Bioorganic and Medicinal Chemistry Letters
1 publication, 6.67%
|
|
|
Letters in Organic Chemistry
1 publication, 6.67%
|
|
|
Russian Chemical Reviews
1 publication, 6.67%
|
|
|
Chemistry of Heterocyclic Compounds
1 publication, 6.67%
|
|
|
ACS Omega
1 publication, 6.67%
|
|
|
Journal of the Indian Chemical Society
1 publication, 6.67%
|
|
|
Russian Journal of Organic Chemistry
1 publication, 6.67%
|
|
|
Журнал органической химии
1 publication, 6.67%
|
|
|
Green Synthesis and Catalysis
1 publication, 6.67%
|
|
|
Russian Chemical Bulletin
1 publication, 6.67%
|
|
|
Organic and Biomolecular Chemistry
1 publication, 6.67%
|
|
|
1
2
3
|
Publishers
|
1
2
3
4
|
|
|
Elsevier
4 publications, 26.67%
|
|
|
MDPI
3 publications, 20%
|
|
|
Springer Nature
2 publications, 13.33%
|
|
|
Bentham Science Publishers Ltd.
1 publication, 6.67%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 6.67%
|
|
|
American Chemical Society (ACS)
1 publication, 6.67%
|
|
|
Pleiades Publishing
1 publication, 6.67%
|
|
|
The Russian Academy of Sciences
1 publication, 6.67%
|
|
|
Royal Society of Chemistry (RSC)
1 publication, 6.67%
|
|
|
1
2
3
4
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
15
Total citations:
15
Citations from 2024:
11
(73%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Aksenov A. et al. Reductive Cleavage of 4′H-Spiro[indole-3,5′-isoxazoles] En Route to 2-(1H-Indol-3-yl)acetamides with Anticancer Activities // Journal of Organic Chemistry. 2022. Vol. 87. No. 21. pp. 13955-13964.
GOST all authors (up to 50)
Copy
Aksenov A., Kirilov N. K., Arutiunov N. A., Aksenov D. A., Kuzminov I. K., Aksenov N. A., Turner D. N., Rogelj S., Kornienko A., Rubin M. Reductive Cleavage of 4′H-Spiro[indole-3,5′-isoxazoles] En Route to 2-(1H-Indol-3-yl)acetamides with Anticancer Activities // Journal of Organic Chemistry. 2022. Vol. 87. No. 21. pp. 13955-13964.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/acs.joc.2c01627
UR - https://doi.org/10.1021/acs.joc.2c01627
TI - Reductive Cleavage of 4′H-Spiro[indole-3,5′-isoxazoles] En Route to 2-(1H-Indol-3-yl)acetamides with Anticancer Activities
T2 - Journal of Organic Chemistry
AU - Aksenov, Alexander V.
AU - Kirilov, Nikita K
AU - Arutiunov, Nikolai A
AU - Aksenov, Dmitrii A
AU - Kuzminov, Iliya K
AU - Aksenov, Nicolai A
AU - Turner, Danielle N
AU - Rogelj, Snezna
AU - Kornienko, Alexander
AU - Rubin, Michael
PY - 2022
DA - 2022/10/19
PB - American Chemical Society (ACS)
SP - 13955-13964
IS - 21
VL - 87
PMID - 36260110
SN - 0022-3263
SN - 1520-6904
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2022_Aksenov,
author = {Alexander V. Aksenov and Nikita K Kirilov and Nikolai A Arutiunov and Dmitrii A Aksenov and Iliya K Kuzminov and Nicolai A Aksenov and Danielle N Turner and Snezna Rogelj and Alexander Kornienko and Michael Rubin},
title = {Reductive Cleavage of 4′H-Spiro[indole-3,5′-isoxazoles] En Route to 2-(1H-Indol-3-yl)acetamides with Anticancer Activities},
journal = {Journal of Organic Chemistry},
year = {2022},
volume = {87},
publisher = {American Chemical Society (ACS)},
month = {oct},
url = {https://doi.org/10.1021/acs.joc.2c01627},
number = {21},
pages = {13955--13964},
doi = {10.1021/acs.joc.2c01627}
}
Cite this
MLA
Copy
Aksenov, Alexander V., et al. “Reductive Cleavage of 4′H-Spiro[indole-3,5′-isoxazoles] En Route to 2-(1H-Indol-3-yl)acetamides with Anticancer Activities.” Journal of Organic Chemistry, vol. 87, no. 21, Oct. 2022, pp. 13955-13964. https://doi.org/10.1021/acs.joc.2c01627.