Copper-Catalyzed Aerobic Oxidative Dehydrogenative Coupling to Access Benzo[c]cinnolines
1
Qingyuan Innovation Laboratory, Quanzhou 362801, China
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Publication type: Journal Article
Publication date: 2024-08-12
scimago Q1
wos Q1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
39133545
Abstract
In this paper, a highly efficient copper-catalyzed oxidative dehydrogenative coupling to obtain benzo[c]cinnolines (up to 100% yield) was developed. It was found that DMAP was a highly efficient ligand for copper-catalyzed oxidation, and molecular oxygen was a green oxidizing agent. In this simple process, various functional groups were tolerated under mild reaction conditions, and the practicality of the process was demonstrated by the preparation of benzo[c]cinnolines on a gram scale and later derivatization.
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Citations from 2025:
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(80%)
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GOST
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Li S. et al. Copper-Catalyzed Aerobic Oxidative Dehydrogenative Coupling to Access Benzo[c]cinnolines // Organic Letters. 2024. Vol. 26. No. 33. pp. 6988-6992.
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Li S., An Y., Zhao W., Huang J., Wen B., Chen X. Copper-Catalyzed Aerobic Oxidative Dehydrogenative Coupling to Access Benzo[c]cinnolines // Organic Letters. 2024. Vol. 26. No. 33. pp. 6988-6992.
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RIS
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TY - JOUR
DO - 10.1021/acs.orglett.4c02315
UR - https://pubs.acs.org/doi/10.1021/acs.orglett.4c02315
TI - Copper-Catalyzed Aerobic Oxidative Dehydrogenative Coupling to Access Benzo[c]cinnolines
T2 - Organic Letters
AU - Li, Shiyun
AU - An, Yan
AU - Zhao, Wei
AU - Huang, Jun
AU - Wen, Bin
AU - Chen, Xingquan
PY - 2024
DA - 2024/08/12
PB - American Chemical Society (ACS)
SP - 6988-6992
IS - 33
VL - 26
PMID - 39133545
SN - 1523-7060
SN - 1523-7052
ER -
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BibTex (up to 50 authors)
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@article{2024_Li,
author = {Shiyun Li and Yan An and Wei Zhao and Jun Huang and Bin Wen and Xingquan Chen},
title = {Copper-Catalyzed Aerobic Oxidative Dehydrogenative Coupling to Access Benzo[c]cinnolines},
journal = {Organic Letters},
year = {2024},
volume = {26},
publisher = {American Chemical Society (ACS)},
month = {aug},
url = {https://pubs.acs.org/doi/10.1021/acs.orglett.4c02315},
number = {33},
pages = {6988--6992},
doi = {10.1021/acs.orglett.4c02315}
}
Cite this
MLA
Copy
Li, Shiyun, et al. “Copper-Catalyzed Aerobic Oxidative Dehydrogenative Coupling to Access Benzo[c]cinnolines.” Organic Letters, vol. 26, no. 33, Aug. 2024, pp. 6988-6992. https://pubs.acs.org/doi/10.1021/acs.orglett.4c02315.