Synthesis and Herbicidal Activities of Novel 3-N-Substituted Amino-6-methyl-4-(3-trifluoromethylphenyl)pyridazine Derivatives
Han Xu
1
,
Xu Hong Hu
1
,
Xiao-Mao Zou
1
,
Bin Liu
1
,
You-Quan Zhu
1
,
Yong Wang
1
,
Fang-Zhong Hu
1
,
Hua-Zheng Yang
1
Publication type: Journal Article
Publication date: 2008-07-08
scimago Q1
wos Q1
SJR: 1.215
CiteScore: 9.3
Impact factor: 6.2
ISSN: 00218561, 15205118
PubMed ID:
18605735
General Chemistry
General Agricultural and Biological Sciences
Abstract
4-(3-Trifluoromethylphenyl)pyridazine is a new series of compounds with bleaching and herbicidal activities. Starting from ethyl 2-(3-trifluoromethylphenyl)acetate, an important intermediate 7 was synthesized in five steps with a moderate total yield of 51.5% in a safe and practical way. Twenty-six novel 3-N-substituted amino-6-methyl-4-(3-trifluoromethylphenyl)pyridazine derivatives were synthesized and evaluated through a Spirodela polyrrhiza test and greenhouse test. Some compounds can completely inhibit Chl at 1 microg/mL and exhibit equal or higher herbicidal activities with the commercial bleaching herbicide diflufenican against dicotyledonous plants at a rate of 75 g/ha.
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Total citations:
38
Citations from 2024:
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(23%)
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GOST
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Xu H. et al. Synthesis and Herbicidal Activities of Novel 3-N-Substituted Amino-6-methyl-4-(3-trifluoromethylphenyl)pyridazine Derivatives // Journal of Agricultural and Food Chemistry. 2008. Vol. 56. No. 15. pp. 6567-6572.
GOST all authors (up to 50)
Copy
Xu H., Hu X. H., Zou X., Liu B., Zhu Y., Wang Y., Hu F., Yang H. Synthesis and Herbicidal Activities of Novel 3-N-Substituted Amino-6-methyl-4-(3-trifluoromethylphenyl)pyridazine Derivatives // Journal of Agricultural and Food Chemistry. 2008. Vol. 56. No. 15. pp. 6567-6572.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/jf800900h
UR - https://doi.org/10.1021/jf800900h
TI - Synthesis and Herbicidal Activities of Novel 3-N-Substituted Amino-6-methyl-4-(3-trifluoromethylphenyl)pyridazine Derivatives
T2 - Journal of Agricultural and Food Chemistry
AU - Xu, Han
AU - Hu, Xu Hong
AU - Zou, Xiao-Mao
AU - Liu, Bin
AU - Zhu, You-Quan
AU - Wang, Yong
AU - Hu, Fang-Zhong
AU - Yang, Hua-Zheng
PY - 2008
DA - 2008/07/08
PB - American Chemical Society (ACS)
SP - 6567-6572
IS - 15
VL - 56
PMID - 18605735
SN - 0021-8561
SN - 1520-5118
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2008_Xu,
author = {Han Xu and Xu Hong Hu and Xiao-Mao Zou and Bin Liu and You-Quan Zhu and Yong Wang and Fang-Zhong Hu and Hua-Zheng Yang},
title = {Synthesis and Herbicidal Activities of Novel 3-N-Substituted Amino-6-methyl-4-(3-trifluoromethylphenyl)pyridazine Derivatives},
journal = {Journal of Agricultural and Food Chemistry},
year = {2008},
volume = {56},
publisher = {American Chemical Society (ACS)},
month = {jul},
url = {https://doi.org/10.1021/jf800900h},
number = {15},
pages = {6567--6572},
doi = {10.1021/jf800900h}
}
Cite this
MLA
Copy
Xu, Han, et al. “Synthesis and Herbicidal Activities of Novel 3-N-Substituted Amino-6-methyl-4-(3-trifluoromethylphenyl)pyridazine Derivatives.” Journal of Agricultural and Food Chemistry, vol. 56, no. 15, Jul. 2008, pp. 6567-6572. https://doi.org/10.1021/jf800900h.