volume 26 issue 2 pages 218-222

2-[(Phenylthio)methyl]pyridine derivatives: new antiinflammatory agents

Fortuna Haviv
Robert W Denet
Raymond J Michaels
James D Ratajczyk
George W Carter
Patrick R. Young
Publication typeJournal Article
Publication date1983-02-01
scimago Q1
wos Q1
SJR1.801
CiteScore11.5
Impact factor6.8
ISSN00222623, 15204804
PubMed ID:  6827539
Drug Discovery
Molecular Medicine
Abstract
2-[(Phenylthio)methyl]pyridine derivatives inhibited the dermal reverse passive Arthus reaction (RPAR) in the rat. In the same model, indomethacin was inactive, and hydrocortisone was active. Compounds Ia-d also significantly reduced exudate volume and white blood cell accumulation in the pleural RPAR. This pattern of activity was similar to that of hydrocortisone and different from that of indomethacin.
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GOST |
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GOST Copy
Haviv F. et al. 2-[(Phenylthio)methyl]pyridine derivatives: new antiinflammatory agents // Journal of Medicinal Chemistry. 1983. Vol. 26. No. 2. pp. 218-222.
GOST all authors (up to 50) Copy
Haviv F., Denet R. W., Michaels R. J., Ratajczyk J. D., Carter G. W., Young P. R. 2-[(Phenylthio)methyl]pyridine derivatives: new antiinflammatory agents // Journal of Medicinal Chemistry. 1983. Vol. 26. No. 2. pp. 218-222.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/jm00356a018
UR - https://doi.org/10.1021/jm00356a018
TI - 2-[(Phenylthio)methyl]pyridine derivatives: new antiinflammatory agents
T2 - Journal of Medicinal Chemistry
AU - Haviv, Fortuna
AU - Denet, Robert W
AU - Michaels, Raymond J
AU - Ratajczyk, James D
AU - Carter, George W
AU - Young, Patrick R.
PY - 1983
DA - 1983/02/01
PB - American Chemical Society (ACS)
SP - 218-222
IS - 2
VL - 26
PMID - 6827539
SN - 0022-2623
SN - 1520-4804
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{1983_Haviv,
author = {Fortuna Haviv and Robert W Denet and Raymond J Michaels and James D Ratajczyk and George W Carter and Patrick R. Young},
title = {2-[(Phenylthio)methyl]pyridine derivatives: new antiinflammatory agents},
journal = {Journal of Medicinal Chemistry},
year = {1983},
volume = {26},
publisher = {American Chemical Society (ACS)},
month = {feb},
url = {https://doi.org/10.1021/jm00356a018},
number = {2},
pages = {218--222},
doi = {10.1021/jm00356a018}
}
MLA
Cite this
MLA Copy
Haviv, Fortuna, et al. “2-[(Phenylthio)methyl]pyridine derivatives: new antiinflammatory agents.” Journal of Medicinal Chemistry, vol. 26, no. 2, Feb. 1983, pp. 218-222. https://doi.org/10.1021/jm00356a018.