Journal of Organic Chemistry, volume 73, issue 4, pages 1620-1623

Versatile and Expeditious Synthesis of Aurones via AuI-Catalyzed Cyclization

Hassina Harkat 1
Aurélien Blanc 1
Jean-Marc Weibel 1
1
 
Laboratoire de Synthèse et Réactivité Organique, associé au CNRS, Institut de Chimie, Université Louis Pasteur, 4 rue Blaise Pascal, 67000 Strasbourg, France ppale@chimie.u-strasbg.fr
Publication typeJournal Article
Publication date2008-01-15
scimago Q2
SJR0.724
CiteScore6.2
Impact factor3.3
ISSN00223263, 15206904
PubMed ID:  18193886
Organic Chemistry
Abstract
Aurones are conveniently formed in a three-step procedure including a goldI-catalyzed cyclization of 2-(1-hydroxyprop-2-ynyl)phenols as a highly regio- and stereoselective key step. A wide diversity of derivatives can be obtained starting from substituted salicylaldehydes. Synthesis of natural 4,6,3',4'-tetramethoxyaurone and structure revision of two natural products (dalmaisione D and 4'-chloroaurone) were achieved.

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