Organic Letters, volume 15, issue 14, pages 3646-3649

A Novel Solvent-Free Approach to Imidazole Containing Nitrogen-Bridgehead Heterocycles

Publication typeJournal Article
Publication date2013-06-27
Journal: Organic Letters
scimago Q1
wos Q1
SJR1.245
CiteScore9.3
Impact factor4.9
ISSN15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A very simple domino reaction under solvent-free conditions of various pyridine-like heterocycles with 1,2-diaza-1,3-dienes produces in good yields imidazo[1,2-a]pyridines, imidazo[1,2-a]quinolines, and imidazo[2,1-a]isoquinolines. The advantage of this one-pot transformation lies in the use of simple pyridine-like compounds without prefunctionalization of the starting heterocycles.

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