Organic Process Research and Development, volume 13, issue 6, pages 1141-1144
Short and Efficient Process for the Synthesis of trans-4-Aminocyclohexanecarboxylic Acid Derivatives
Pankaj S Patil
1
,
Ulhas S. Mahajan
1
,
Swapnil P Sonawane
1
,
Mukund K. Gurjar
1
1
API R & D Centre, Emcure Pharmaceuticals Ltd., ITBT Park, Phase-II, MIDC, Hinjewadi, Pune - 411057, India
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Publication type: Journal Article
Publication date: 2009-10-14
scimago Q1
SJR: 0.900
CiteScore: 6.9
Impact factor: 3.1
ISSN: 10836160, 1520586X
Organic Chemistry
Physical and Theoretical Chemistry
Abstract
This contribution relates to an industrially feasible process for the preparation of isomerically pure trans-4-amino-1-cyclohexanecarboxylic acid derivatives that are useful building blocks in the synthesis of several pharmacologically active compounds such as glimepiride, L-370518.
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