ACS Biomaterials Science and Engineering

, volume 1 , issue 2 , pages 64-78

Nanotherapy for Cancer: Targeting and Multifunctionality in the Future of Cancer Therapies

Asiri Ediriwickrema ¹

W. Mark Saltzman ¹

Hide authors affiliations Show authors affiliations: 1 affiliation

Department of Biomedical Engineering, Yale University, 55 Prospect Street, MEC 414, New Haven, Connecticut 06511, United States |

Publication type: Journal Article

Publication date: 2015-02-01

American Chemical Society (ACS)

ACS Biomaterials Science and Engineering

scimago Q1

wos Q2

SJR: 1.105

CiteScore: 9.7

Impact factor: 5.5

ISSN: 23739878

DOI: 10.1021/ab500084g

Copy DOI

PubMed ID: 25984571

Biomaterials

Biomedical Engineering

Abstract

Cancer continues to be a prevalent and lethal disease, despite advances in tumor biology research and chemotherapy development. Major obstacles in cancer treatment arise from tumor heterogeneity, drug resistance, and systemic toxicities. Nanoscale delivery systems, or nanotherapies, are increasing in importance as vehicles for antineoplastic agents because of their potential for targeting and multifunctionality. We discuss the current field of cancer therapy and potential strategies for addressing obstacles in cancer treatment with nanotherapies. Specifically, we review the strategies for rationally designing nanoparticles for targeted, multimodal delivery of therapeutic agents.

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Ediriwickrema A., Saltzman W. M. Nanotherapy for Cancer: Targeting and Multifunctionality in the Future of Cancer Therapies // ACS Biomaterials Science and Engineering. 2015. Vol. 1. No. 2. pp. 64-78.

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RIS |

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RIS Copy

TY - JOUR

DO - 10.1021/ab500084g

UR - https://doi.org/10.1021/ab500084g

TI - Nanotherapy for Cancer: Targeting and Multifunctionality in the Future of Cancer Therapies

T2 - ACS Biomaterials Science and Engineering

AU - Ediriwickrema, Asiri

AU - Saltzman, W. Mark

PY - 2015

DA - 2015/02/01

PB - American Chemical Society (ACS)

SP - 64-78

IS - 2

VL - 1

PMID - 25984571

SN - 2373-9878

ER -

BibTex |

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BibTex (up to 50 authors) Copy

@article{2015_Ediriwickrema,

author = {Asiri Ediriwickrema and W. Mark Saltzman},

title = {Nanotherapy for Cancer: Targeting and Multifunctionality in the Future of Cancer Therapies},

journal = {ACS Biomaterials Science and Engineering},

year = {2015},

volume = {1},

publisher = {American Chemical Society (ACS)},

month = {feb},

url = {https://doi.org/10.1021/ab500084g},

number = {2},

pages = {64--78},

doi = {10.1021/ab500084g}

}

MLA

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MLA Copy

Ediriwickrema, Asiri, and W. Mark Saltzman. “Nanotherapy for Cancer: Targeting and Multifunctionality in the Future of Cancer Therapies.” ACS Biomaterials Science and Engineering, vol. 1, no. 2, Feb. 2015, pp. 64-78. https://doi.org/10.1021/ab500084g.

Publisher

American Chemical Society (ACS)

Journal

ACS Biomaterials Science and Engineering

scimago Q1

wos Q2

SJR

1.105

CiteScore

9.7

Impact factor

5.5

ISSN

23739878 (Print, Electronic)