Open Access
Biocompatibility of Resorbable Polymers: A Historical Perspective and Framework for the Future
Publication type: Journal Article
Publication date: 2019-03-11
scimago Q1
wos Q1
SJR: 1.142
CiteScore: 9.2
Impact factor: 5.4
ISSN: 15257797, 15264602
PubMed ID:
30855137
Materials Chemistry
Polymers and Plastics
Bioengineering
Biomaterials
Abstract
The history of resorbable polymers containing glycolide, lactide, ε-caprolactone and trimethylene carbonate, with a special emphasis being placed on the time frame of the 1960s-1990s is described. Reviewing the history is valuable when looking into the future perspectives regarding how and where these monomers should be used. This story includes scientific evaluations indicating that these polymers are safe to use in medical devices, while the design of the medical device is not considered in this report. In particular, we present the data regarding the tissue response to implanted polymers, as well as the toxicity and pharmacokinetics of their degradation products. In the translation of these polymers from "the bench to the bedside," various challenges have been faced by surgeons, medical doctors, biologists, material engineers and polymer chemists. This Perspective highlights the visionary role played by the pioneers, addressing the problems that occurred on a case by case basis in translational medicine.
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152
Total citations:
152
Citations from 2024:
54
(35%)
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GOST
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Pappalardo D., Mathisen T., Finne-Wistrand A. Biocompatibility of Resorbable Polymers: A Historical Perspective and Framework for the Future // Biomacromolecules. 2019. Vol. 20. No. 4. pp. 1465-1477.
GOST all authors (up to 50)
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Pappalardo D., Mathisen T., Finne-Wistrand A. Biocompatibility of Resorbable Polymers: A Historical Perspective and Framework for the Future // Biomacromolecules. 2019. Vol. 20. No. 4. pp. 1465-1477.
Cite this
RIS
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TY - JOUR
DO - 10.1021/acs.biomac.9b00159
UR - https://doi.org/10.1021/acs.biomac.9b00159
TI - Biocompatibility of Resorbable Polymers: A Historical Perspective and Framework for the Future
T2 - Biomacromolecules
AU - Pappalardo, Daniela
AU - Mathisen, Torbjörn
AU - Finne-Wistrand, Anna
PY - 2019
DA - 2019/03/11
PB - American Chemical Society (ACS)
SP - 1465-1477
IS - 4
VL - 20
PMID - 30855137
SN - 1525-7797
SN - 1526-4602
ER -
Cite this
BibTex (up to 50 authors)
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@article{2019_Pappalardo,
author = {Daniela Pappalardo and Torbjörn Mathisen and Anna Finne-Wistrand},
title = {Biocompatibility of Resorbable Polymers: A Historical Perspective and Framework for the Future},
journal = {Biomacromolecules},
year = {2019},
volume = {20},
publisher = {American Chemical Society (ACS)},
month = {mar},
url = {https://doi.org/10.1021/acs.biomac.9b00159},
number = {4},
pages = {1465--1477},
doi = {10.1021/acs.biomac.9b00159}
}
Cite this
MLA
Copy
Pappalardo, Daniela, et al. “Biocompatibility of Resorbable Polymers: A Historical Perspective and Framework for the Future.” Biomacromolecules, vol. 20, no. 4, Mar. 2019, pp. 1465-1477. https://doi.org/10.1021/acs.biomac.9b00159.
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