Organocatalytic Asymmetric Synthesis of Spirooxindole Embedded Oxazolidines
Publication type: Journal Article
Publication date: 2021-08-27
scimago Q2
wos Q1
SJR: 0.737
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
PubMed ID:
34448585
Organic Chemistry
Abstract
The first organocatalytic asymmetric synthesis of spirooxindole embedded oxazolidines has been developed via a domino reaction involving hemiaminal formation, followed by an unprecedented aza-Michael reaction between isatin derived N-Boc ketimines and γ-hydroxy enones. A quinine derived bifunctional squaramide catalyst was found to be efficient for this reaction, and the products were obtained in good diastereoselectivity and with high enantioselectivity.
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Metrics
17
Total citations:
17
Citations from 2024:
8
(47.06%)
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GOST
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Parida C. et al. Organocatalytic Asymmetric Synthesis of Spirooxindole Embedded Oxazolidines // Journal of Organic Chemistry. 2021. Vol. 86. No. 18. pp. 13082-13091.
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Parida C., Mondal B., Ghosh A., Chandra Pan S. Organocatalytic Asymmetric Synthesis of Spirooxindole Embedded Oxazolidines // Journal of Organic Chemistry. 2021. Vol. 86. No. 18. pp. 13082-13091.
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RIS
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TY - JOUR
DO - 10.1021/acs.joc.1c00644
UR - https://doi.org/10.1021/acs.joc.1c00644
TI - Organocatalytic Asymmetric Synthesis of Spirooxindole Embedded Oxazolidines
T2 - Journal of Organic Chemistry
AU - Parida, Chandrakanta
AU - Mondal, Buddhadeb
AU - Ghosh, Animesh
AU - Chandra Pan, Subhas
PY - 2021
DA - 2021/08/27
PB - American Chemical Society (ACS)
SP - 13082-13091
IS - 18
VL - 86
PMID - 34448585
SN - 0022-3263
SN - 1520-6904
ER -
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BibTex (up to 50 authors)
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@article{2021_Parida,
author = {Chandrakanta Parida and Buddhadeb Mondal and Animesh Ghosh and Subhas Chandra Pan},
title = {Organocatalytic Asymmetric Synthesis of Spirooxindole Embedded Oxazolidines},
journal = {Journal of Organic Chemistry},
year = {2021},
volume = {86},
publisher = {American Chemical Society (ACS)},
month = {aug},
url = {https://doi.org/10.1021/acs.joc.1c00644},
number = {18},
pages = {13082--13091},
doi = {10.1021/acs.joc.1c00644}
}
Cite this
MLA
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Parida, Chandrakanta, et al. “Organocatalytic Asymmetric Synthesis of Spirooxindole Embedded Oxazolidines.” Journal of Organic Chemistry, vol. 86, no. 18, Aug. 2021, pp. 13082-13091. https://doi.org/10.1021/acs.joc.1c00644.