Metal-Free Annulation of 2-Nitrobenzyl Alcohols and Tetrahydroisoquinolines toward the Divergent Synthesis of Quinazolinones and Quinazolinethiones
Duc Ly
1, 2
,
Thao T Nguyen
1, 2
,
Cam T H Tran
1, 2
,
Vy P T Nguyen
1, 2
,
Khang X Nguyen
1, 2
,
Phuc Pham
1, 2
,
Nhan T H Le
1, 2
,
Tung T. Nguyen
1, 2
,
Nam T. S. Phan
1, 2
Publication type: Journal Article
Publication date: 2021-12-17
scimago Q2
wos Q1
SJR: 0.737
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
PubMed ID:
34918926
Organic Chemistry
Abstract
A simple metal-free method for the synthesis of quinazolinones from commercially available 2-nitrobenzyl alcohols and tetrahydroisoquinolines is developed. The reaction conditions were tolerant of an array of functionalities such as halogen, tertiary amine, protected alcohol, and ester groups. Under nearly identical conditions, quinazolinethiones were obtained in the presence of elemental sulfur and suitable mediators.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
4
|
|
|
Organic and Biomolecular Chemistry
4 publications, 23.53%
|
|
|
Journal of Organic Chemistry
2 publications, 11.76%
|
|
|
Chinese Journal of Organic Chemistry
1 publication, 5.88%
|
|
|
Synthesis
1 publication, 5.88%
|
|
|
Progress in Heterocyclic Chemistry
1 publication, 5.88%
|
|
|
Journal of Organometallic Chemistry
1 publication, 5.88%
|
|
|
Molecules
1 publication, 5.88%
|
|
|
Journal of Electronic Materials
1 publication, 5.88%
|
|
|
Russian Chemical Reviews
1 publication, 5.88%
|
|
|
Organic Letters
1 publication, 5.88%
|
|
|
Angewandte Chemie - International Edition
1 publication, 5.88%
|
|
|
Angewandte Chemie
1 publication, 5.88%
|
|
|
Advanced Synthesis and Catalysis
1 publication, 5.88%
|
|
|
1
2
3
4
|
Publishers
|
1
2
3
4
|
|
|
Royal Society of Chemistry (RSC)
4 publications, 23.53%
|
|
|
American Chemical Society (ACS)
3 publications, 17.65%
|
|
|
Wiley
3 publications, 17.65%
|
|
|
Elsevier
2 publications, 11.76%
|
|
|
Shanghai Institute of Organic Chemistry
1 publication, 5.88%
|
|
|
Georg Thieme Verlag KG
1 publication, 5.88%
|
|
|
MDPI
1 publication, 5.88%
|
|
|
Springer Nature
1 publication, 5.88%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 5.88%
|
|
|
1
2
3
4
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
17
Total citations:
17
Citations from 2024:
11
(64.7%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Ly D. et al. Metal-Free Annulation of 2-Nitrobenzyl Alcohols and Tetrahydroisoquinolines toward the Divergent Synthesis of Quinazolinones and Quinazolinethiones // Journal of Organic Chemistry. 2021. Vol. 87. No. 1. pp. 103-113.
GOST all authors (up to 50)
Copy
Ly D., Nguyen T. T., Tran C. T. H., Nguyen V. P. T., Nguyen K. X., Pham P., Le N. T. H., Nguyen T. T., Phan N. T. S. Metal-Free Annulation of 2-Nitrobenzyl Alcohols and Tetrahydroisoquinolines toward the Divergent Synthesis of Quinazolinones and Quinazolinethiones // Journal of Organic Chemistry. 2021. Vol. 87. No. 1. pp. 103-113.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/acs.joc.1c02017
UR - https://doi.org/10.1021/acs.joc.1c02017
TI - Metal-Free Annulation of 2-Nitrobenzyl Alcohols and Tetrahydroisoquinolines toward the Divergent Synthesis of Quinazolinones and Quinazolinethiones
T2 - Journal of Organic Chemistry
AU - Ly, Duc
AU - Nguyen, Thao T
AU - Tran, Cam T H
AU - Nguyen, Vy P T
AU - Nguyen, Khang X
AU - Pham, Phuc
AU - Le, Nhan T H
AU - Nguyen, Tung T.
AU - Phan, Nam T. S.
PY - 2021
DA - 2021/12/17
PB - American Chemical Society (ACS)
SP - 103-113
IS - 1
VL - 87
PMID - 34918926
SN - 0022-3263
SN - 1520-6904
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Ly,
author = {Duc Ly and Thao T Nguyen and Cam T H Tran and Vy P T Nguyen and Khang X Nguyen and Phuc Pham and Nhan T H Le and Tung T. Nguyen and Nam T. S. Phan},
title = {Metal-Free Annulation of 2-Nitrobenzyl Alcohols and Tetrahydroisoquinolines toward the Divergent Synthesis of Quinazolinones and Quinazolinethiones},
journal = {Journal of Organic Chemistry},
year = {2021},
volume = {87},
publisher = {American Chemical Society (ACS)},
month = {dec},
url = {https://doi.org/10.1021/acs.joc.1c02017},
number = {1},
pages = {103--113},
doi = {10.1021/acs.joc.1c02017}
}
Cite this
MLA
Copy
Ly, Duc, et al. “Metal-Free Annulation of 2-Nitrobenzyl Alcohols and Tetrahydroisoquinolines toward the Divergent Synthesis of Quinazolinones and Quinazolinethiones.” Journal of Organic Chemistry, vol. 87, no. 1, Dec. 2021, pp. 103-113. https://doi.org/10.1021/acs.joc.1c02017.