Multicomponent Assembly of Bicyclic Aza-peroxides Catalyzed by Samarium Complexes and Their Cytotoxic Activity
Natalia N Makhmudiyarova
1
,
Irina R. Ishmukhametova
1
,
Ekaterina S. Mescheryakova
1
,
E S Meshcheryakova
1
,
Lilya Dzhemileva
2
,
Usein M Dzhemilev
2
Publication type: Journal Article
Publication date: 2023-08-09
scimago Q2
wos Q1
SJR: 0.737
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
PubMed ID:
37557189
Organic Chemistry
Abstract
An original strategy toward bridged tetraoxazaspirobicycloalkanes was developed. The synthesis is based on a three-component condensation–cyclization reaction of primary arylamines with 1,1′-peroxybis (1-hydroperoxycycloalkanes) and pentane-1,5-dial catalyzed by Sm(NO3)3·6H2O. The structures and conformations of the products were determined by X-ray diffraction analysis and 1H and 13C NMR spectroscopy. High cytotoxic activity and biological potential toward ferroptosis induction were found for the synthesized bicyclic aza-peroxides.
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Makhmudiyarova N. N. et al. Multicomponent Assembly of Bicyclic Aza-peroxides Catalyzed by Samarium Complexes and Their Cytotoxic Activity // Journal of Organic Chemistry. 2023. Vol. 88. No. 16. pp. 11473-11485.
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Makhmudiyarova N. N., Ishmukhametova I. R., Ishmukhametova I. R., Tyumkina T. V., Mescheryakova E. S., Meshcheryakova E. S., Dzhemileva L., Dzhemileva L. U., D'yakonov V. A., Terent'ev A. O., Dzhemilev U. M. Multicomponent Assembly of Bicyclic Aza-peroxides Catalyzed by Samarium Complexes and Their Cytotoxic Activity // Journal of Organic Chemistry. 2023. Vol. 88. No. 16. pp. 11473-11485.
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TY - JOUR
DO - 10.1021/acs.joc.3c00555
UR - https://pubs.acs.org/doi/10.1021/acs.joc.3c00555
TI - Multicomponent Assembly of Bicyclic Aza-peroxides Catalyzed by Samarium Complexes and Their Cytotoxic Activity
T2 - Journal of Organic Chemistry
AU - Makhmudiyarova, Natalia N
AU - Ishmukhametova, Irina R.
AU - Ishmukhametova, I. R.
AU - Tyumkina, Tatyana V
AU - Mescheryakova, Ekaterina S.
AU - Meshcheryakova, E S
AU - Dzhemileva, Lilya
AU - Dzhemileva, Lilya U.
AU - D'yakonov, Vladimir A
AU - Terent'ev, Alexander O.
AU - Dzhemilev, Usein M
PY - 2023
DA - 2023/08/09
PB - American Chemical Society (ACS)
SP - 11473-11485
IS - 16
VL - 88
PMID - 37557189
SN - 0022-3263
SN - 1520-6904
ER -
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BibTex (up to 50 authors)
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@article{2023_Makhmudiyarova,
author = {Natalia N Makhmudiyarova and Irina R. Ishmukhametova and I. R. Ishmukhametova and Tatyana V Tyumkina and Ekaterina S. Mescheryakova and E S Meshcheryakova and Lilya Dzhemileva and Lilya U. Dzhemileva and Vladimir A D'yakonov and Alexander O. Terent'ev and Usein M Dzhemilev},
title = {Multicomponent Assembly of Bicyclic Aza-peroxides Catalyzed by Samarium Complexes and Their Cytotoxic Activity},
journal = {Journal of Organic Chemistry},
year = {2023},
volume = {88},
publisher = {American Chemical Society (ACS)},
month = {aug},
url = {https://pubs.acs.org/doi/10.1021/acs.joc.3c00555},
number = {16},
pages = {11473--11485},
doi = {10.1021/acs.joc.3c00555}
}
Cite this
MLA
Copy
Makhmudiyarova, Natalia N., et al. “Multicomponent Assembly of Bicyclic Aza-peroxides Catalyzed by Samarium Complexes and Their Cytotoxic Activity.” Journal of Organic Chemistry, vol. 88, no. 16, Aug. 2023, pp. 11473-11485. https://pubs.acs.org/doi/10.1021/acs.joc.3c00555.