Concise Stereoselective Total Synthesis of (−)-Hedycoropyran A
2
YS Life Science Co., Ltd., 207, Sujeong-ro, Jangan-myeon, Hwaseong-si, Gyeonggi-do 18581, Republic of Korea
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Publication type: Journal Article
Publication date: 2023-11-28
scimago Q2
wos Q1
SJR: 0.737
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
PubMed ID:
38014885
Organic Chemistry
Abstract
A concise and stereoselective total synthesis of (-)-hedycoropyran A was accomplished in a substrate-controlled manner from a readily available alkene. Highlights of the synthesis include a highly diastereoselective dehydrogenative cycloetherification to construct the trans-2-aryl-6-alkyl-3,6-dihydro-2H-pyran framework and late-stage substrate-controlled trans-dihydroxylation at C(3,4).
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Ahn B. et al. Concise Stereoselective Total Synthesis of (−)-Hedycoropyran A // Journal of Organic Chemistry. 2023. Vol. 88. No. 24. pp. 17172-17180.
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Ahn B., Lee R., Kim H., Lee D. Concise Stereoselective Total Synthesis of (−)-Hedycoropyran A // Journal of Organic Chemistry. 2023. Vol. 88. No. 24. pp. 17172-17180.
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TY - JOUR
DO - 10.1021/acs.joc.3c02046
UR - https://pubs.acs.org/doi/10.1021/acs.joc.3c02046
TI - Concise Stereoselective Total Synthesis of (−)-Hedycoropyran A
T2 - Journal of Organic Chemistry
AU - Ahn, Byeongyeon
AU - Lee, Ryangha
AU - Kim, Hyoungsu
AU - Lee, Dongjoo
PY - 2023
DA - 2023/11/28
PB - American Chemical Society (ACS)
SP - 17172-17180
IS - 24
VL - 88
PMID - 38014885
SN - 0022-3263
SN - 1520-6904
ER -
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BibTex (up to 50 authors)
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@article{2023_Ahn,
author = {Byeongyeon Ahn and Ryangha Lee and Hyoungsu Kim and Dongjoo Lee},
title = {Concise Stereoselective Total Synthesis of (−)-Hedycoropyran A},
journal = {Journal of Organic Chemistry},
year = {2023},
volume = {88},
publisher = {American Chemical Society (ACS)},
month = {nov},
url = {https://pubs.acs.org/doi/10.1021/acs.joc.3c02046},
number = {24},
pages = {17172--17180},
doi = {10.1021/acs.joc.3c02046}
}
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MLA
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Ahn, Byeongyeon, et al. “Concise Stereoselective Total Synthesis of (−)-Hedycoropyran A.” Journal of Organic Chemistry, vol. 88, no. 24, Nov. 2023, pp. 17172-17180. https://pubs.acs.org/doi/10.1021/acs.joc.3c02046.