volume 89 issue 9 pages 6027-6039

Precise Synthesis of Diastereomers of Spiro-oxindole Derivatives through Dynamic Covalent Transformation

Publication typeJournal Article
Publication date2024-04-17
scimago Q2
wos Q1
SJR0.737
CiteScore6.1
Impact factor3.6
ISSN00223263, 15206904
Organic Chemistry
Abstract
In this study, [1+2+2] cyclization of tryptamine-derived isocyanides with 3-ylideneoxindoles was systematically investigated. A series of structurally complex spiro-oxindole derivatives were obtained. Characteristic dynamic covalent chemistry was observed and confirmed by experiments and density functional theory calculation. Through the regulation of the solvent, temperature, and time, the precise and stereodivergent synthesis of spiro-oxindoles was achieved.
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GOST Copy
Liu X. et al. Precise Synthesis of Diastereomers of Spiro-oxindole Derivatives through Dynamic Covalent Transformation // Journal of Organic Chemistry. 2024. Vol. 89. No. 9. pp. 6027-6039.
GOST all authors (up to 50) Copy
Liu X., Liu X., Zhang J., Zhang J. D., Ji S. J., Xu X. Precise Synthesis of Diastereomers of Spiro-oxindole Derivatives through Dynamic Covalent Transformation // Journal of Organic Chemistry. 2024. Vol. 89. No. 9. pp. 6027-6039.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1021/acs.joc.3c02966
UR - https://pubs.acs.org/doi/10.1021/acs.joc.3c02966
TI - Precise Synthesis of Diastereomers of Spiro-oxindole Derivatives through Dynamic Covalent Transformation
T2 - Journal of Organic Chemistry
AU - Liu, Xiao-Qian
AU - Liu, Xiaoqian
AU - Zhang, Jian-dong
AU - Zhang, Jian Dong
AU - Ji, Shun Jun
AU - Xu, Xiaoping
PY - 2024
DA - 2024/04/17
PB - American Chemical Society (ACS)
SP - 6027-6039
IS - 9
VL - 89
PMID - 38630554
SN - 0022-3263
SN - 1520-6904
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{2024_Liu,
author = {Xiao-Qian Liu and Xiaoqian Liu and Jian-dong Zhang and Jian Dong Zhang and Shun Jun Ji and Xiaoping Xu},
title = {Precise Synthesis of Diastereomers of Spiro-oxindole Derivatives through Dynamic Covalent Transformation},
journal = {Journal of Organic Chemistry},
year = {2024},
volume = {89},
publisher = {American Chemical Society (ACS)},
month = {apr},
url = {https://pubs.acs.org/doi/10.1021/acs.joc.3c02966},
number = {9},
pages = {6027--6039},
doi = {10.1021/acs.joc.3c02966}
}
MLA
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MLA Copy
Liu, Xiao-Qian, et al. “Precise Synthesis of Diastereomers of Spiro-oxindole Derivatives through Dynamic Covalent Transformation.” Journal of Organic Chemistry, vol. 89, no. 9, Apr. 2024, pp. 6027-6039. https://pubs.acs.org/doi/10.1021/acs.joc.3c02966.
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