Palladium-Catalyzed Domino Carboetherification Reactions: Synthesis of Bis-Heterocycles Bearing Isoxazoline and Methyleneindole Motifs
Feifei Jin
1
,
Qing Wu
1
,
Shuaijie Wu
1
,
Huiwen Dong
1
,
Huijun Dong
1
,
Yanru He
1
,
Youzhou He
1
,
Jing Sun
1
,
Chaoguo Yan
1
,
Wenbo Li
2
,
Lei Wang
1
Publication type: Journal Article
Publication date: 2024-12-18
scimago Q2
wos Q1
SJR: 0.737
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
PubMed ID:
39692079
Abstract
A novel and highly efficient Pd-catalyzed approach for the synthesis of bis-heterocycles featuring both isoxazoline and methyleneindole motifs is demonstrated. The in situ formation of vinyl Pd(II) species through an alkyne-tethered carbamoyl chloride cyclization is crucial, and the innovative Pd-catalyzed carboetherification of β,γ-unsaturated oximes with vinyl Pd(II) species has been developed. This method is not only operationally straightforward but also exhibits a broad substrate scope and excellent functional group tolerance.
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Total citations:
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Citations from 2024:
4
(100%)
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GOST
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Jin F. et al. Palladium-Catalyzed Domino Carboetherification Reactions: Synthesis of Bis-Heterocycles Bearing Isoxazoline and Methyleneindole Motifs // Journal of Organic Chemistry. 2024. Vol. 90. No. 1. pp. 742-752.
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Jin F., Wu Q., Wu S., Dong H., Dong H., He Y., He Y., Sun J., Yan C., Li W., Wang L. Palladium-Catalyzed Domino Carboetherification Reactions: Synthesis of Bis-Heterocycles Bearing Isoxazoline and Methyleneindole Motifs // Journal of Organic Chemistry. 2024. Vol. 90. No. 1. pp. 742-752.
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TY - JOUR
DO - 10.1021/acs.joc.4c02679
UR - https://pubs.acs.org/doi/10.1021/acs.joc.4c02679
TI - Palladium-Catalyzed Domino Carboetherification Reactions: Synthesis of Bis-Heterocycles Bearing Isoxazoline and Methyleneindole Motifs
T2 - Journal of Organic Chemistry
AU - Jin, Feifei
AU - Wu, Qing
AU - Wu, Shuaijie
AU - Dong, Huiwen
AU - Dong, Huijun
AU - He, Yanru
AU - He, Youzhou
AU - Sun, Jing
AU - Yan, Chaoguo
AU - Li, Wenbo
AU - Wang, Lei
PY - 2024
DA - 2024/12/18
PB - American Chemical Society (ACS)
SP - 742-752
IS - 1
VL - 90
PMID - 39692079
SN - 0022-3263
SN - 1520-6904
ER -
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BibTex (up to 50 authors)
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@article{2024_Jin,
author = {Feifei Jin and Qing Wu and Shuaijie Wu and Huiwen Dong and Huijun Dong and Yanru He and Youzhou He and Jing Sun and Chaoguo Yan and Wenbo Li and Lei Wang},
title = {Palladium-Catalyzed Domino Carboetherification Reactions: Synthesis of Bis-Heterocycles Bearing Isoxazoline and Methyleneindole Motifs},
journal = {Journal of Organic Chemistry},
year = {2024},
volume = {90},
publisher = {American Chemical Society (ACS)},
month = {dec},
url = {https://pubs.acs.org/doi/10.1021/acs.joc.4c02679},
number = {1},
pages = {742--752},
doi = {10.1021/acs.joc.4c02679}
}
Cite this
MLA
Copy
Jin, Feifei, et al. “Palladium-Catalyzed Domino Carboetherification Reactions: Synthesis of Bis-Heterocycles Bearing Isoxazoline and Methyleneindole Motifs.” Journal of Organic Chemistry, vol. 90, no. 1, Dec. 2024, pp. 742-752. https://pubs.acs.org/doi/10.1021/acs.joc.4c02679.