American Chemical Society (ACS)
Journal of Organic Chemistry
,  volume 80 ,  issue 9 ,  pages 4611-4617

Regioselective Metal-Free One-Pot Synthesis of Functionalized 2-Aminothiophene Derivatives

Publication type: Journal Article
Publication date: 2015-04-23
American Chemical Society (ACS)
scimago Q2
wos Q1
SJR: 0.737
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
Organic Chemistry
Abstract
A facile metal-free synthesis of 2-aminothiophene derivatives by the reaction of 2-ynals with thioamides in alcohols has been developed. This transformation allows the assembly of 2-aminothienyl ether derivatives via a well-designed aldol condensation/regioselective intramolecular cyclization/conjugate addition cascade reaction and provides a straightforward synthetic protocol for constructing 2,3,5-trisubstituted 2-aminothiophenes.
Found 
Found 
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GOST |
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GOST Copy
Luo X. et al. Regioselective Metal-Free One-Pot Synthesis of Functionalized 2-Aminothiophene Derivatives // Journal of Organic Chemistry. 2015. Vol. 80. No. 9. pp. 4611-4617.
GOST all authors (up to 50) Copy
Luo X., Ge L. S., An X. L., Jin J. H., Wang Yu., Sun P., Deng W. Regioselective Metal-Free One-Pot Synthesis of Functionalized 2-Aminothiophene Derivatives // Journal of Organic Chemistry. 2015. Vol. 80. No. 9. pp. 4611-4617.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/acs.joc.5b00488
UR - https://doi.org/10.1021/acs.joc.5b00488
TI - Regioselective Metal-Free One-Pot Synthesis of Functionalized 2-Aminothiophene Derivatives
T2 - Journal of Organic Chemistry
AU - Luo, Xiao-yan
AU - Ge, Li Shi
AU - An, Xing Lan
AU - Jin, Jing Hai
AU - Wang, Yu
AU - Sun, Pei-Pei
AU - Deng, Weiping
PY - 2015
DA - 2015/04/23
PB - American Chemical Society (ACS)
SP - 4611-4617
IS - 9
VL - 80
PMID - 25880135
SN - 0022-3263
SN - 1520-6904
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2015_Luo,
author = {Xiao-yan Luo and Li Shi Ge and Xing Lan An and Jing Hai Jin and Yu Wang and Pei-Pei Sun and Weiping Deng},
title = {Regioselective Metal-Free One-Pot Synthesis of Functionalized 2-Aminothiophene Derivatives},
journal = {Journal of Organic Chemistry},
year = {2015},
volume = {80},
publisher = {American Chemical Society (ACS)},
month = {apr},
url = {https://doi.org/10.1021/acs.joc.5b00488},
number = {9},
pages = {4611--4617},
doi = {10.1021/acs.joc.5b00488}
}
MLA
Cite this
MLA Copy
Luo, Xiao-yan, et al. “Regioselective Metal-Free One-Pot Synthesis of Functionalized 2-Aminothiophene Derivatives.” Journal of Organic Chemistry, vol. 80, no. 9, Apr. 2015, pp. 4611-4617. https://doi.org/10.1021/acs.joc.5b00488.