American Chemical Society (ACS)
Journal of Organic Chemistry
,  volume 82 ,  issue 6 ,  pages 3011-3018

One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine

Publication type: Journal Article
Publication date: 2017-03-08
American Chemical Society (ACS)
scimago Q2
wos Q1
SJR: 0.737
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
Organic Chemistry
Abstract
Indolo[3,2-c]quinolones have been efficiently synthesized via an acid-mediated, one-pot, three-component condensation of arylhydrazines, o-aminoacetophenones, and triazines or nitriles. The synthetic application of this method is showcased by the concise synthesis of isocryptolepine alkaloid and a series of its synthetic analogues with demonstrated cancer cell antiproliferative activities.
Found 
Found 
12 citations
Aksenov Aleksandr
🥼 🤝
DSc in Chemistry, professor
243 publications,  2 187 citations,  15 reviews
h-index: 24
North Caucasus Federal University
North Caucasus Federal University
Research interests
Medicinal Chemistry
Organic Chemistry
2 citations
Beloglazkina Elena
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Lomonosov Moscow State University
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A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
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North Caucasus Federal University
North Caucasus Federal University
Kuban State University
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Heterocyclic compounds
Malononitrile
Selenoamides
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Zagidullin Almaz
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PhD in Chemistry
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A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
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Chemistry of organic and organoelement compounds; chemistry of polymers; production of materials
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Nesterov Nikolay
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Boreskov Institute of Catalysis of the Siberian Branch of the Russian Academy of Sciences
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MALYUGA VLADIMIR
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N.D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences
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Kantyukov Artyom
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A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
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Kazan Federal University
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Postovsky Institute of Organic Synthesis of the Ural Branch of the Russian Academy of Sciences
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Tikhomirov Alexander
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A.E. Favorsky Irkutsk Institute of Chemistry of the Siberian Branch of the Russian Academy of Sciences
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Saint Petersburg State University
Saint Petersburg State University
I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences
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GOST |
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GOST Copy
Aksenov A. et al. One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine // Journal of Organic Chemistry. 2017. Vol. 82. No. 6. pp. 3011-3018.
GOST all authors (up to 50) Copy
Aksenov A., Aksenov D. A., Orazova N. A., Aksenov N. A., Griaznov G. D., Carvalho A., Kiss R., MATHIEU V., Kornienko A., Rubin M. One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine // Journal of Organic Chemistry. 2017. Vol. 82. No. 6. pp. 3011-3018.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/acs.joc.6b03084
UR - https://doi.org/10.1021/acs.joc.6b03084
TI - One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine
T2 - Journal of Organic Chemistry
AU - Aksenov, Alexander V.
AU - Aksenov, Dmitrii A
AU - Orazova, Naila A
AU - Aksenov, Nicolai A.
AU - Griaznov, Georgii D
AU - Carvalho, Annelise
AU - Kiss, Robert
AU - MATHIEU, VÉRONIQUE
AU - Kornienko, Alexander
AU - Rubin, Michael
PY - 2017
DA - 2017/03/08
PB - American Chemical Society (ACS)
SP - 3011-3018
IS - 6
VL - 82
PMID - 28253622
SN - 0022-3263
SN - 1520-6904
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2017_Aksenov,
author = {Alexander V. Aksenov and Dmitrii A Aksenov and Naila A Orazova and Nicolai A. Aksenov and Georgii D Griaznov and Annelise Carvalho and Robert Kiss and VÉRONIQUE MATHIEU and Alexander Kornienko and Michael Rubin},
title = {One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine},
journal = {Journal of Organic Chemistry},
year = {2017},
volume = {82},
publisher = {American Chemical Society (ACS)},
month = {mar},
url = {https://doi.org/10.1021/acs.joc.6b03084},
number = {6},
pages = {3011--3018},
doi = {10.1021/acs.joc.6b03084}
}
MLA
Cite this
MLA Copy
Aksenov, Alexander V., et al. “One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine.” Journal of Organic Chemistry, vol. 82, no. 6, Mar. 2017, pp. 3011-3018. https://doi.org/10.1021/acs.joc.6b03084.