volume 84 issue 13 pages 8731-8742

Synthesis of Quinolines and Isoquinolines via Site-Selective, Domino Benzannulation of 2- and 3-Chloropyridyl Ynones with Nitromethane

Publication typeJournal Article
Publication date2019-06-14
scimago Q2
wos Q1
SJR0.737
CiteScore6.1
Impact factor3.6
ISSN00223263, 15206904
Organic Chemistry
Abstract
An approach of general applicability to diverse quinolines and isoquinolines via a tactic that utilizes the recursive anion from nitromethane as a 1C-connector to stitch easily and appropriately crafted pyridyl ynones through a transition-metal-free, tandem Michael addition-SNAr process is delineated. The straightforwardness, one-pot operation, and good yields mark this methodology for wider exploitation in targeting more embellished quinolines and isoquinolines and complex platforms embodying these moieties.
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GOST Copy
Beesu M., Mehta G. Synthesis of Quinolines and Isoquinolines via Site-Selective, Domino Benzannulation of 2- and 3-Chloropyridyl Ynones with Nitromethane // Journal of Organic Chemistry. 2019. Vol. 84. No. 13. pp. 8731-8742.
GOST all authors (up to 50) Copy
Beesu M., Mehta G. Synthesis of Quinolines and Isoquinolines via Site-Selective, Domino Benzannulation of 2- and 3-Chloropyridyl Ynones with Nitromethane // Journal of Organic Chemistry. 2019. Vol. 84. No. 13. pp. 8731-8742.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/acs.joc.9b00950
UR - https://doi.org/10.1021/acs.joc.9b00950
TI - Synthesis of Quinolines and Isoquinolines via Site-Selective, Domino Benzannulation of 2- and 3-Chloropyridyl Ynones with Nitromethane
T2 - Journal of Organic Chemistry
AU - Beesu, Mallesh
AU - Mehta, Goverdhan
PY - 2019
DA - 2019/06/14
PB - American Chemical Society (ACS)
SP - 8731-8742
IS - 13
VL - 84
PMID - 31199134
SN - 0022-3263
SN - 1520-6904
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2019_Beesu,
author = {Mallesh Beesu and Goverdhan Mehta},
title = {Synthesis of Quinolines and Isoquinolines via Site-Selective, Domino Benzannulation of 2- and 3-Chloropyridyl Ynones with Nitromethane},
journal = {Journal of Organic Chemistry},
year = {2019},
volume = {84},
publisher = {American Chemical Society (ACS)},
month = {jun},
url = {https://doi.org/10.1021/acs.joc.9b00950},
number = {13},
pages = {8731--8742},
doi = {10.1021/acs.joc.9b00950}
}
MLA
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MLA Copy
Beesu, Mallesh, and Goverdhan Mehta. “Synthesis of Quinolines and Isoquinolines via Site-Selective, Domino Benzannulation of 2- and 3-Chloropyridyl Ynones with Nitromethane.” Journal of Organic Chemistry, vol. 84, no. 13, Jun. 2019, pp. 8731-8742. https://doi.org/10.1021/acs.joc.9b00950.
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