Gd(III)-Grafted Detonation Nanodiamonds for MRI Contrast Enhancement
Publication type: Journal Article
Publication date: 2019-01-10
scimago Q1
wos Q3
SJR: 0.914
CiteScore: 6.2
Impact factor: 3.2
ISSN: 19327447, 19327455
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Physical and Theoretical Chemistry
General Energy
Abstract
We report on the first 1H NMR relaxation and magnetic resonance imaging (MRI) study of aqueous suspensions of detonation nanodiamond (DND) grafted by Gd(III) ions. In contrast to Gd(III)–ND conjugates implemented via organic species, Gd(III) ions were directly grafted to the surface of DND particles. Such Gd(III)-grafted DND particles significantly shorten spin–lattice (T1) and spin–spin (T2) relaxation times of water protons providing relaxivities of r1 = 33.4 and r2 = 332 mM–1 s–1, which considerably exceed most of those reported in the literature. It makes the Gd(III)-grafted DND complexes attractive for use as novel MRI contrast agents.
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62
Total citations:
62
Citations from 2024:
19
(30%)
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Panich A. et al. Gd(III)-Grafted Detonation Nanodiamonds for MRI Contrast Enhancement // Journal of Physical Chemistry C. 2019. Vol. 123. No. 4. pp. 2627-2631.
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Yudina E., Aleksenskii A. E., Vul' A. Gd(III)-Grafted Detonation Nanodiamonds for MRI Contrast Enhancement // Journal of Physical Chemistry C. 2019. Vol. 123. No. 4. pp. 2627-2631.
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RIS
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TY - JOUR
DO - 10.1021/acs.jpcc.8b11655
UR - https://doi.org/10.1021/acs.jpcc.8b11655
TI - Gd(III)-Grafted Detonation Nanodiamonds for MRI Contrast Enhancement
T2 - Journal of Physical Chemistry C
AU - Yudina, Elena
AU - Aleksenskii, Alexander E.
AU - Vul', A.Ya.
PY - 2019
DA - 2019/01/10
PB - American Chemical Society (ACS)
SP - 2627-2631
IS - 4
VL - 123
SN - 1932-7447
SN - 1932-7455
ER -
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BibTex (up to 50 authors)
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@article{2019_Panich,
author = {Elena Yudina and Alexander E. Aleksenskii and A.Ya. Vul'},
title = {Gd(III)-Grafted Detonation Nanodiamonds for MRI Contrast Enhancement},
journal = {Journal of Physical Chemistry C},
year = {2019},
volume = {123},
publisher = {American Chemical Society (ACS)},
month = {jan},
url = {https://doi.org/10.1021/acs.jpcc.8b11655},
number = {4},
pages = {2627--2631},
doi = {10.1021/acs.jpcc.8b11655}
}
Cite this
MLA
Copy
Panich, A.M., et al. “Gd(III)-Grafted Detonation Nanodiamonds for MRI Contrast Enhancement.” Journal of Physical Chemistry C, vol. 123, no. 4, Jan. 2019, pp. 2627-2631. https://doi.org/10.1021/acs.jpcc.8b11655.
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