Boron Dipyrromethene-Based Phototheranostics for Near Infrared Fluorescent and Photoacoustic Imaging-Guided Synchronous Photodynamic and Photothermal Therapy of Cancer
Xuejian Xing
1
,
Yang Ke
1
,
Baoling Li
1
,
Siyi Tan
2
,
Jianing Yi
3
,
Xiangcao Li
1
,
E Pang
1
,
Benhua Wang
1
,
Xiangzhi Song
1
,
Minhuan Lan
1
2
Huazhi Medical Laboratory Co., Ltd., 618 Heping Road, Changsha 410125, P.R. China
|
Publication type: Journal Article
Publication date: 2022-08-18
scimago Q1
wos Q1
SJR: 1.394
CiteScore: 8.7
Impact factor: 4.6
ISSN: 19487185
PubMed ID:
35980815
Physical and Theoretical Chemistry
General Materials Science
Abstract
The regulation of photochemical properties of phototheranostics, especially the absorption, fluorescence, singlet oxygen (1O2) generation, and photothermal conversion efficiency, is a hot research topic. Here, we designed and synthesized four boron dipyrromethene (BODIPY) derivatives with high absorption coefficients and intense fluorescence in the near-infrared (NIR) region. The substituted electron-donating group significantly improved 1O2 generation and fluorescence of BODIPYs, whereas the electron-withdrawing group boosts photothermal conversion. These hydrophobic BODIPYs were further coated with DSPE-PEG-2000 to form water dispersible nanoparticles (NPs). Among these BODIPY NPs, the B-OMe-NPs with methoxyl substituted at the meso-position showed the highest 1O2 generation, a photothermal conversion efficiency of 66.5%, and an NIR fluorescence peak at 809 nm. In vitro and in vivo experiments demonstrated that B-OMe-NPs might be used for NIR fluorescent and photoacoustic imaging-guided photodynamic and photothermal therapy of cancer.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
|
|
|
Chinese Chemical Letters
2 publications, 12.5%
|
|
|
International Journal of Molecular Sciences
1 publication, 6.25%
|
|
|
Organic Letters
1 publication, 6.25%
|
|
|
Materials Today Bio
1 publication, 6.25%
|
|
|
Chemical Engineering Journal
1 publication, 6.25%
|
|
|
Molecular Cancer
1 publication, 6.25%
|
|
|
Organic and Biomolecular Chemistry
1 publication, 6.25%
|
|
|
Coordination Chemistry Reviews
1 publication, 6.25%
|
|
|
Journal of Molecular Structure
1 publication, 6.25%
|
|
|
MedComm
1 publication, 6.25%
|
|
|
Advanced Functional Materials
1 publication, 6.25%
|
|
|
Russian Chemical Reviews
1 publication, 6.25%
|
|
|
ACS Applied Nano Materials
1 publication, 6.25%
|
|
|
Journal of Physical Chemistry Letters
1 publication, 6.25%
|
|
|
Journal of Colloid and Interface Science
1 publication, 6.25%
|
|
|
1
2
|
Publishers
|
1
2
3
4
5
6
7
|
|
|
Elsevier
7 publications, 43.75%
|
|
|
American Chemical Society (ACS)
3 publications, 18.75%
|
|
|
Wiley
2 publications, 12.5%
|
|
|
MDPI
1 publication, 6.25%
|
|
|
Springer Nature
1 publication, 6.25%
|
|
|
Royal Society of Chemistry (RSC)
1 publication, 6.25%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 6.25%
|
|
|
1
2
3
4
5
6
7
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
16
Total citations:
16
Citations from 2024:
8
(50%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Xing X. et al. Boron Dipyrromethene-Based Phototheranostics for Near Infrared Fluorescent and Photoacoustic Imaging-Guided Synchronous Photodynamic and Photothermal Therapy of Cancer // Journal of Physical Chemistry Letters. 2022. Vol. 13. No. 34. pp. 7939-7946.
GOST all authors (up to 50)
Copy
Xing X., Ke Y., Li B., Tan S., Yi J., Li X., Pang E., Wang B., Song X., Lan M. Boron Dipyrromethene-Based Phototheranostics for Near Infrared Fluorescent and Photoacoustic Imaging-Guided Synchronous Photodynamic and Photothermal Therapy of Cancer // Journal of Physical Chemistry Letters. 2022. Vol. 13. No. 34. pp. 7939-7946.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/acs.jpclett.2c02122
UR - https://doi.org/10.1021/acs.jpclett.2c02122
TI - Boron Dipyrromethene-Based Phototheranostics for Near Infrared Fluorescent and Photoacoustic Imaging-Guided Synchronous Photodynamic and Photothermal Therapy of Cancer
T2 - Journal of Physical Chemistry Letters
AU - Xing, Xuejian
AU - Ke, Yang
AU - Li, Baoling
AU - Tan, Siyi
AU - Yi, Jianing
AU - Li, Xiangcao
AU - Pang, E
AU - Wang, Benhua
AU - Song, Xiangzhi
AU - Lan, Minhuan
PY - 2022
DA - 2022/08/18
PB - American Chemical Society (ACS)
SP - 7939-7946
IS - 34
VL - 13
PMID - 35980815
SN - 1948-7185
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2022_Xing,
author = {Xuejian Xing and Yang Ke and Baoling Li and Siyi Tan and Jianing Yi and Xiangcao Li and E Pang and Benhua Wang and Xiangzhi Song and Minhuan Lan},
title = {Boron Dipyrromethene-Based Phototheranostics for Near Infrared Fluorescent and Photoacoustic Imaging-Guided Synchronous Photodynamic and Photothermal Therapy of Cancer},
journal = {Journal of Physical Chemistry Letters},
year = {2022},
volume = {13},
publisher = {American Chemical Society (ACS)},
month = {aug},
url = {https://doi.org/10.1021/acs.jpclett.2c02122},
number = {34},
pages = {7939--7946},
doi = {10.1021/acs.jpclett.2c02122}
}
Cite this
MLA
Copy
Xing, Xuejian, et al. “Boron Dipyrromethene-Based Phototheranostics for Near Infrared Fluorescent and Photoacoustic Imaging-Guided Synchronous Photodynamic and Photothermal Therapy of Cancer.” Journal of Physical Chemistry Letters, vol. 13, no. 34, Aug. 2022, pp. 7939-7946. https://doi.org/10.1021/acs.jpclett.2c02122.