Organometallics, volume 34, issue 18, pages 4491-4506

Synthesis, Structure, DNA/Protein Binding, and Anticancer Activity of Some Half-Sandwich Cyclometalated Rh(III) and Ir(III) Complexes

Mukhopadhyay Sujay
Gupta Rakesh Kumar
Paitandi Rajendra Prasad
Rana Nishant Kumar
Sharma Gunjan
Koch Biplob
Rana Love Karan 1
Hundal* Maninder Singh 1
Publication typeJournal Article
Publication date2015-09-17
Journal: Organometallics
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor2.8
ISSN02767333, 15206041
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Abstract
The Schiff base ligands benzylidene(4-tert-butylphenyl)amine 4-methyl ester (L1), (4-nitrobenzylidene)(4-tert-butylphenyl)amine (L2), and (4-cyanobenzylidene)(4-tert-butylphenyl)amine (L3) and the new series of cyclometalated mononuclear piano-stool complexes [(η5-C5Me5)RhCl(L1)] (1), [(η5-C5Me5)RhCl(L2)] (2), [(η5-C5Me5)RhCl(L3)] (3), [(η5-C5Me5)IrCl(L1)] (4), [(η5-C5Me5)IrCl(L2)] (5), and [(η5-C5Me5)IrCl(L3)] (6) have been synthesized. The ligands L1–L3 and complexes 1–6 have been thoroughly characterized by satisfactory elemental analyses, spectral studies (ESI-MS, IR, 1H and 13C NMR, UV–vis), and structures of 1–3 authenticated by X-ray single-crystal analyses. Efficient binding of 1–6 with calf thymus DNA (CT DNA) have been established by UV–vis and emission spectroscopic studies. Protein binding (bovine serum albumin, BSA) has been investigated by UV–vis, fluorescence, synchronous, and 3D fluorescence spectroscopy. Binding of the complexes with DNA through minor groove and hydrophobic interaction wi...

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Mukhopadhyay S. et al. Synthesis, Structure, DNA/Protein Binding, and Anticancer Activity of Some Half-Sandwich Cyclometalated Rh(III) and Ir(III) Complexes // Organometallics. 2015. Vol. 34. No. 18. pp. 4491-4506.
GOST all authors (up to 50) Copy
Mukhopadhyay S., Gupta R. K., Paitandi R. P., Rana N. K., Sharma G., Koch B., Rana L. K., Hundal* M. S., Pandey D. S. Synthesis, Structure, DNA/Protein Binding, and Anticancer Activity of Some Half-Sandwich Cyclometalated Rh(III) and Ir(III) Complexes // Organometallics. 2015. Vol. 34. No. 18. pp. 4491-4506.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/acs.organomet.5b00475
UR - https://doi.org/10.1021%2Facs.organomet.5b00475
TI - Synthesis, Structure, DNA/Protein Binding, and Anticancer Activity of Some Half-Sandwich Cyclometalated Rh(III) and Ir(III) Complexes
T2 - Organometallics
AU - Mukhopadhyay, Sujay
AU - Gupta, Rakesh Kumar
AU - Paitandi, Rajendra Prasad
AU - Rana, Nishant Kumar
AU - Rana, Love Karan
AU - Hundal*, Maninder Singh
AU - Sharma, Gunjan
AU - Koch, Biplob
AU - Pandey, Daya Shankar
PY - 2015
DA - 2015/09/17 00:00:00
PB - American Chemical Society (ACS)
SP - 4491-4506
IS - 18
VL - 34
SN - 0276-7333
SN - 1520-6041
ER -
BibTex |
Cite this
BibTex Copy
@article{2015_Mukhopadhyay,
author = {Sujay Mukhopadhyay and Rakesh Kumar Gupta and Rajendra Prasad Paitandi and Nishant Kumar Rana and Love Karan Rana and Maninder Singh Hundal* and Gunjan Sharma and Biplob Koch and Daya Shankar Pandey},
title = {Synthesis, Structure, DNA/Protein Binding, and Anticancer Activity of Some Half-Sandwich Cyclometalated Rh(III) and Ir(III) Complexes},
journal = {Organometallics},
year = {2015},
volume = {34},
publisher = {American Chemical Society (ACS)},
month = {sep},
url = {https://doi.org/10.1021%2Facs.organomet.5b00475},
number = {18},
pages = {4491--4506},
doi = {10.1021/acs.organomet.5b00475}
}
MLA
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MLA Copy
Mukhopadhyay, Sujay, et al. “Synthesis, Structure, DNA/Protein Binding, and Anticancer Activity of Some Half-Sandwich Cyclometalated Rh(III) and Ir(III) Complexes.” Organometallics, vol. 34, no. 18, Sep. 2015, pp. 4491-4506. https://doi.org/10.1021%2Facs.organomet.5b00475.
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