Organic Letters, volume 22, issue 5, pages 1903-1907

Diastereoselective Synthesis of Cycloheptannelated Indoles via Lewis-Acid-Catalyzed (4 + 3)-Cyclization of Donor–Acceptor Cyclopropanes

Publication typeJournal Article
Publication date2020-02-17
Journal: Organic Letters
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor5.2
ISSN15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
An efficient and straightforward Lewis-acid-mediated stereoselective (4 + 3)-cyclization of indole-substituted alkylidene malonates and donor-acceptor cyclopropanes has been developed involving the Friedel-Crafts/Michael addition cyclization cascade. This reaction provides a mild and effective method for the construction of synthetically and structurally interesting functionalized cycloheptannelated indoles.

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GOST |
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GOST Copy
Li B. Q. et al. Diastereoselective Synthesis of Cycloheptannelated Indoles via Lewis-Acid-Catalyzed (4 + 3)-Cyclization of Donor–Acceptor Cyclopropanes // Organic Letters. 2020. Vol. 22. No. 5. pp. 1903-1907.
GOST all authors (up to 50) Copy
Li B. Q., Qiu Z. W., Ma A., Peng J., Feng N., Du J. Y., Pan H., Zhang X., Xu X. Diastereoselective Synthesis of Cycloheptannelated Indoles via Lewis-Acid-Catalyzed (4 + 3)-Cyclization of Donor–Acceptor Cyclopropanes // Organic Letters. 2020. Vol. 22. No. 5. pp. 1903-1907.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1021/acs.orglett.0c00248
UR - https://doi.org/10.1021/acs.orglett.0c00248
TI - Diastereoselective Synthesis of Cycloheptannelated Indoles via Lewis-Acid-Catalyzed (4 + 3)-Cyclization of Donor–Acceptor Cyclopropanes
T2 - Organic Letters
AU - Qiu, Zong Wang
AU - Ma, Ai-Jun
AU - Feng, Na
AU - Pan, Han-Peng
AU - Li, Bao Qiong
AU - Peng, Jin-Bao
AU - Du, Ji Yuan
AU - Zhang, Xiang-Zhi
AU - Xu, Xuetao
PY - 2020
DA - 2020/02/17 00:00:00
PB - American Chemical Society (ACS)
SP - 1903-1907
IS - 5
VL - 22
SN - 1523-7060
SN - 1523-7052
ER -
BibTex |
Cite this
BibTex Copy
@article{2020_Li,
author = {Zong Wang Qiu and Ai-Jun Ma and Na Feng and Han-Peng Pan and Bao Qiong Li and Jin-Bao Peng and Ji Yuan Du and Xiang-Zhi Zhang and Xuetao Xu},
title = {Diastereoselective Synthesis of Cycloheptannelated Indoles via Lewis-Acid-Catalyzed (4 + 3)-Cyclization of Donor–Acceptor Cyclopropanes},
journal = {Organic Letters},
year = {2020},
volume = {22},
publisher = {American Chemical Society (ACS)},
month = {feb},
url = {https://doi.org/10.1021/acs.orglett.0c00248},
number = {5},
pages = {1903--1907},
doi = {10.1021/acs.orglett.0c00248}
}
MLA
Cite this
MLA Copy
Li, Bao Qiong, et al. “Diastereoselective Synthesis of Cycloheptannelated Indoles via Lewis-Acid-Catalyzed (4 + 3)-Cyclization of Donor–Acceptor Cyclopropanes.” Organic Letters, vol. 22, no. 5, Feb. 2020, pp. 1903-1907. https://doi.org/10.1021/acs.orglett.0c00248.
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