Iodine-Mediated Multicomponent Cascade Cyclization and Sulfenylation/Selenation: Synthesis of Imidazo[2,1-a]isoquinoline Derivatives
Publication type: Journal Article
Publication date: 2022-06-13
scimago Q1
wos Q1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
35696662
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A novel multicomponent cascade cyclization and sulfenylation/selenation using aryl methyl ketones, isoquinolin-1-amine, and sodium arylsulfinates/1,2-diphenyldiselane to synthesize imidazo[2,1-a]isoquinoline derivatives in one-pot via the construction of two C-N bonds and one C-S/C-Se bond has been reported. This multicomponent reaction realizes simultaneous C(sp3)-H amination and sulfenylation/selenation, avoiding complicated prior substrate preparation. This process has simple operating conditions and good substrate compatibility.
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20
Total citations:
20
Citations from 2025:
5
(25%)
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MLA
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GOST
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Wang L. S. et al. Iodine-Mediated Multicomponent Cascade Cyclization and Sulfenylation/Selenation: Synthesis of Imidazo[2,1-a]isoquinoline Derivatives // Organic Letters. 2022. Vol. 24. No. 24. pp. 4449-4453.
GOST all authors (up to 50)
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Wang L. S., Zhou Y., Lei S. G., YU X., Huang C., Wu Y., Wu A. Iodine-Mediated Multicomponent Cascade Cyclization and Sulfenylation/Selenation: Synthesis of Imidazo[2,1-a]isoquinoline Derivatives // Organic Letters. 2022. Vol. 24. No. 24. pp. 4449-4453.
Cite this
RIS
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TY - JOUR
DO - 10.1021/acs.orglett.2c01681
UR - https://doi.org/10.1021/acs.orglett.2c01681
TI - Iodine-Mediated Multicomponent Cascade Cyclization and Sulfenylation/Selenation: Synthesis of Imidazo[2,1-a]isoquinoline Derivatives
T2 - Organic Letters
AU - Wang, Li Sheng
AU - Zhou, You
AU - Lei, Shuang Gui
AU - YU, XIAO-XIAO
AU - Huang, Chun
AU - Wu, Yan-Dong
AU - Wu, An-Xin
PY - 2022
DA - 2022/06/13
PB - American Chemical Society (ACS)
SP - 4449-4453
IS - 24
VL - 24
PMID - 35696662
SN - 1523-7060
SN - 1523-7052
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2022_Wang,
author = {Li Sheng Wang and You Zhou and Shuang Gui Lei and XIAO-XIAO YU and Chun Huang and Yan-Dong Wu and An-Xin Wu},
title = {Iodine-Mediated Multicomponent Cascade Cyclization and Sulfenylation/Selenation: Synthesis of Imidazo[2,1-a]isoquinoline Derivatives},
journal = {Organic Letters},
year = {2022},
volume = {24},
publisher = {American Chemical Society (ACS)},
month = {jun},
url = {https://doi.org/10.1021/acs.orglett.2c01681},
number = {24},
pages = {4449--4453},
doi = {10.1021/acs.orglett.2c01681}
}
Cite this
MLA
Copy
Wang, Li Sheng, et al. “Iodine-Mediated Multicomponent Cascade Cyclization and Sulfenylation/Selenation: Synthesis of Imidazo[2,1-a]isoquinoline Derivatives.” Organic Letters, vol. 24, no. 24, Jun. 2022, pp. 4449-4453. https://doi.org/10.1021/acs.orglett.2c01681.