Organic Letters, volume 24, issue 30, pages 5509-5512

3,4-Annulated Indoles via Tandem Cyclopropane Ring-Opening/Conia-ene and Michael Addition/Conia-ene Reactions

Shane R Cochrane 1
M A Kerr 1
1
 
Department of Chemistry, the University of Western Ontario, London, ON N6A 5B7, Canada
Publication typeJournal Article
Publication date2022-07-21
Journal: Organic Letters
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor5.2
ISSN15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
4-Alkynyl indoles, when treated with a benzylidene malonate or a donor-acceptor cyclopropane in the presence of a zinc halide, furnished 3,4-hexannylated or 3,4-heptannulated products, respectively, in fair to excellent yields. The reaction proceeds via a tandem addition/Conia-ene cyclization.

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GOST Copy
Cochrane S. R., Kerr M. A. 3,4-Annulated Indoles via Tandem Cyclopropane Ring-Opening/Conia-ene and Michael Addition/Conia-ene Reactions // Organic Letters. 2022. Vol. 24. No. 30. pp. 5509-5512.
GOST all authors (up to 50) Copy
Cochrane S. R., Kerr M. A. 3,4-Annulated Indoles via Tandem Cyclopropane Ring-Opening/Conia-ene and Michael Addition/Conia-ene Reactions // Organic Letters. 2022. Vol. 24. No. 30. pp. 5509-5512.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1021/acs.orglett.2c01810
UR - https://doi.org/10.1021/acs.orglett.2c01810
TI - 3,4-Annulated Indoles via Tandem Cyclopropane Ring-Opening/Conia-ene and Michael Addition/Conia-ene Reactions
T2 - Organic Letters
AU - Cochrane, Shane R
AU - Kerr, M A
PY - 2022
DA - 2022/07/21 00:00:00
PB - American Chemical Society (ACS)
SP - 5509-5512
IS - 30
VL - 24
SN - 1523-7060
SN - 1523-7052
ER -
BibTex |
Cite this
BibTex Copy
@article{2022_Cochrane,
author = {Shane R Cochrane and M A Kerr},
title = {3,4-Annulated Indoles via Tandem Cyclopropane Ring-Opening/Conia-ene and Michael Addition/Conia-ene Reactions},
journal = {Organic Letters},
year = {2022},
volume = {24},
publisher = {American Chemical Society (ACS)},
month = {jul},
url = {https://doi.org/10.1021/acs.orglett.2c01810},
number = {30},
pages = {5509--5512},
doi = {10.1021/acs.orglett.2c01810}
}
MLA
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MLA Copy
Cochrane, Shane R., and M A Kerr. “3,4-Annulated Indoles via Tandem Cyclopropane Ring-Opening/Conia-ene and Michael Addition/Conia-ene Reactions.” Organic Letters, vol. 24, no. 30, Jul. 2022, pp. 5509-5512. https://doi.org/10.1021/acs.orglett.2c01810.
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