Rhodium-Promoted C–H Activation/Annulation between DNA-Linked Terminal Alkyne and Aromatic Acid: A Finding from the Selection Outcomes
Yuhan Lv
1, 2
,
Min Wu
3
,
Weiwei Lu
2
,
Weiwei Lu Weiwei Lu
2
,
Meiying Cui
4
,
Jiaxiang Liu
4
,
Wei Yi
3
,
Xuan Wang
4
,
Xiaojie Lu
2, 5
4
Alphama Biotechnology Suzhou Co., Ltd., 108 Yuxin Road, Suzhou City, Jiangsu Province 215123, China
|
Publication type: Journal Article
Publication date: 2024-06-04
scimago Q1
wos Q1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
38833318
Abstract
Inspired by previous selection outcomes, we investigated and developed a rhodium-promoted C-H activation/annulation reaction of DNA-linked terminal alkynes and aromatic acids. This reaction exhibits excellent efficiency with high conversions and a broad substrate scope. Most importantly, the unique DEL-compatible conditions provide a better scenario for yielding an isocoumarin scaffold compared to conventional organic reaction conditions, and this newly developed on-DNA method has confirmed its feasibility in preparing DNA-encoded libraries.
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8
Total citations:
8
Citations from 2024:
8
(100%)
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GOST
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Lv Y. et al. Rhodium-Promoted C–H Activation/Annulation between DNA-Linked Terminal Alkyne and Aromatic Acid: A Finding from the Selection Outcomes // Organic Letters. 2024. Vol. 26. No. 23. pp. 4958-4962.
GOST all authors (up to 50)
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Lv Y., Wu M., Lu W., Weiwei Lu W. L., Cui M., Liu J., Yi W., Wang X., Lu X. Rhodium-Promoted C–H Activation/Annulation between DNA-Linked Terminal Alkyne and Aromatic Acid: A Finding from the Selection Outcomes // Organic Letters. 2024. Vol. 26. No. 23. pp. 4958-4962.
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RIS
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TY - JOUR
DO - 10.1021/acs.orglett.4c01553
UR - https://pubs.acs.org/doi/10.1021/acs.orglett.4c01553
TI - Rhodium-Promoted C–H Activation/Annulation between DNA-Linked Terminal Alkyne and Aromatic Acid: A Finding from the Selection Outcomes
T2 - Organic Letters
AU - Lv, Yuhan
AU - Wu, Min
AU - Lu, Weiwei
AU - Weiwei Lu, Weiwei Lu
AU - Cui, Meiying
AU - Liu, Jiaxiang
AU - Yi, Wei
AU - Wang, Xuan
AU - Lu, Xiaojie
PY - 2024
DA - 2024/06/04
PB - American Chemical Society (ACS)
SP - 4958-4962
IS - 23
VL - 26
PMID - 38833318
SN - 1523-7060
SN - 1523-7052
ER -
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BibTex (up to 50 authors)
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@article{2024_Lv,
author = {Yuhan Lv and Min Wu and Weiwei Lu and Weiwei Lu Weiwei Lu and Meiying Cui and Jiaxiang Liu and Wei Yi and Xuan Wang and Xiaojie Lu},
title = {Rhodium-Promoted C–H Activation/Annulation between DNA-Linked Terminal Alkyne and Aromatic Acid: A Finding from the Selection Outcomes},
journal = {Organic Letters},
year = {2024},
volume = {26},
publisher = {American Chemical Society (ACS)},
month = {jun},
url = {https://pubs.acs.org/doi/10.1021/acs.orglett.4c01553},
number = {23},
pages = {4958--4962},
doi = {10.1021/acs.orglett.4c01553}
}
Cite this
MLA
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Lv, Yuhan, et al. “Rhodium-Promoted C–H Activation/Annulation between DNA-Linked Terminal Alkyne and Aromatic Acid: A Finding from the Selection Outcomes.” Organic Letters, vol. 26, no. 23, Jun. 2024, pp. 4958-4962. https://pubs.acs.org/doi/10.1021/acs.orglett.4c01553.
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