A Tandem Approach to Functionalized Carbazoles from Indoles via Two Successive Regioselective Oxidative Heck Reactions Followed by Thermal Electrocyclization
1
Department
of Pharmaceutical
Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research, S. A. S. Nagar, Punjab 160062, India
|
Publication type: Journal Article
Publication date: 2015-09-24
scimago Q1
wos Q1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
26402033
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A direct one-pot approach to the synthesis of carbazoles (mono-, di-, and trisubstituted) and α-carbolines from readily available indoles or 7-azaindoles and alkenes is described. Based on mechanistic studies, the tandem reaction follows the sequence: palladium-catalyzed regioselective C-3 alkenylation/palladium-catalyzed C-2 alkenylation/thermal electrocyclization.
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99
Total citations:
99
Citations from 2024:
12
(12.12%)
Cite this
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MLA
Cite this
GOST
Copy
Laha J. K., Dayal N. A Tandem Approach to Functionalized Carbazoles from Indoles via Two Successive Regioselective Oxidative Heck Reactions Followed by Thermal Electrocyclization // Organic Letters. 2015. Vol. 17. No. 19. pp. 4742-4745.
GOST all authors (up to 50)
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Laha J. K., Dayal N. A Tandem Approach to Functionalized Carbazoles from Indoles via Two Successive Regioselective Oxidative Heck Reactions Followed by Thermal Electrocyclization // Organic Letters. 2015. Vol. 17. No. 19. pp. 4742-4745.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/acs.orglett.5b02265
UR - https://doi.org/10.1021/acs.orglett.5b02265
TI - A Tandem Approach to Functionalized Carbazoles from Indoles via Two Successive Regioselective Oxidative Heck Reactions Followed by Thermal Electrocyclization
T2 - Organic Letters
AU - Laha, Joydev K.
AU - Dayal, Neetu
PY - 2015
DA - 2015/09/24
PB - American Chemical Society (ACS)
SP - 4742-4745
IS - 19
VL - 17
PMID - 26402033
SN - 1523-7060
SN - 1523-7052
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2015_Laha,
author = {Joydev K. Laha and Neetu Dayal},
title = {A Tandem Approach to Functionalized Carbazoles from Indoles via Two Successive Regioselective Oxidative Heck Reactions Followed by Thermal Electrocyclization},
journal = {Organic Letters},
year = {2015},
volume = {17},
publisher = {American Chemical Society (ACS)},
month = {sep},
url = {https://doi.org/10.1021/acs.orglett.5b02265},
number = {19},
pages = {4742--4745},
doi = {10.1021/acs.orglett.5b02265}
}
Cite this
MLA
Copy
Laha, Joydev K., and Neetu Dayal. “A Tandem Approach to Functionalized Carbazoles from Indoles via Two Successive Regioselective Oxidative Heck Reactions Followed by Thermal Electrocyclization.” Organic Letters, vol. 17, no. 19, Sep. 2015, pp. 4742-4745. https://doi.org/10.1021/acs.orglett.5b02265.