Pd-Catalyzed Intramolecular Cyclization via Direct C–H Addition to Nitriles: Skeletal Diverse Synthesis of Fused Polycyclic Indoles
Publication type: Journal Article
Publication date: 2016-09-14
scimago Q1
wos Q1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
27626643
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
The first example of Pd-catalyzed intramolecular C-H addition of indoles bearing cyanohydrin components at the C(3), C(2), and N(1) positions to nitriles is described. A wide range of functionalized partially saturated carbazoles, tetrahydropyrido[1,2-a]indole, and carbazoles can be prepared in good to excellent yields under the optimal conditions. In addition, fused polycyclic indoles with seven- or eight-membered rings can also be formed smoothly.
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Metrics
43
Total citations:
43
Citations from 2024:
5
(11.63%)
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MLA
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GOST
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Wang T. et al. Pd-Catalyzed Intramolecular Cyclization via Direct C–H Addition to Nitriles: Skeletal Diverse Synthesis of Fused Polycyclic Indoles // Organic Letters. 2016. Vol. 18. No. 19. pp. 5002-5005.
GOST all authors (up to 50)
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Wang T., Zhao L., Zhang Y., LIAO W. Pd-Catalyzed Intramolecular Cyclization via Direct C–H Addition to Nitriles: Skeletal Diverse Synthesis of Fused Polycyclic Indoles // Organic Letters. 2016. Vol. 18. No. 19. pp. 5002-5005.
Cite this
RIS
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TY - JOUR
DO - 10.1021/acs.orglett.6b02460
UR - https://doi.org/10.1021/acs.orglett.6b02460
TI - Pd-Catalyzed Intramolecular Cyclization via Direct C–H Addition to Nitriles: Skeletal Diverse Synthesis of Fused Polycyclic Indoles
T2 - Organic Letters
AU - Wang, Ting-Ting
AU - Zhao, Lang
AU - Zhang, Yan-Jing
AU - LIAO, WEIWEI
PY - 2016
DA - 2016/09/14
PB - American Chemical Society (ACS)
SP - 5002-5005
IS - 19
VL - 18
PMID - 27626643
SN - 1523-7060
SN - 1523-7052
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2016_Wang,
author = {Ting-Ting Wang and Lang Zhao and Yan-Jing Zhang and WEIWEI LIAO},
title = {Pd-Catalyzed Intramolecular Cyclization via Direct C–H Addition to Nitriles: Skeletal Diverse Synthesis of Fused Polycyclic Indoles},
journal = {Organic Letters},
year = {2016},
volume = {18},
publisher = {American Chemical Society (ACS)},
month = {sep},
url = {https://doi.org/10.1021/acs.orglett.6b02460},
number = {19},
pages = {5002--5005},
doi = {10.1021/acs.orglett.6b02460}
}
Cite this
MLA
Copy
Wang, Ting-Ting, et al. “Pd-Catalyzed Intramolecular Cyclization via Direct C–H Addition to Nitriles: Skeletal Diverse Synthesis of Fused Polycyclic Indoles.” Organic Letters, vol. 18, no. 19, Sep. 2016, pp. 5002-5005. https://doi.org/10.1021/acs.orglett.6b02460.