Bromide-Mediated C–H Bond Functionalization: Intermolecular Annulation of Phenylethanone Derivatives with Alkynes for the Synthesis of 1-Naphthols
Publication type: Journal Article
Publication date: 2017-11-17
scimago Q1
wos Q1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
29148795
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
Bromide-mediated intermolecular annulation of phenylethanone derivatives with alkynes has been developed, which allows for the regioselective formation of polysubstituted 1-naphthols. The usage of readily available bromine catalyst, broad substrate scope, and mild conditions make this protocol very practical. Mechanistic investigations reveal that the bromination of phenylethanone derivatives occurs to yield bromo-substituted intermediates, which react in situ with alkynes to furnish the desired 1-naphthols.
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Total citations:
41
Citations from 2024:
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(9.76%)
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GOST
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Lu T. et al. Bromide-Mediated C–H Bond Functionalization: Intermolecular Annulation of Phenylethanone Derivatives with Alkynes for the Synthesis of 1-Naphthols // Organic Letters. 2017. Vol. 19. No. 23. pp. 6344-6347.
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Lu T., Jiang Ya. T., Ma F. P., Tang Z. J., Liu K., Wang Y., Wang B. Bromide-Mediated C–H Bond Functionalization: Intermolecular Annulation of Phenylethanone Derivatives with Alkynes for the Synthesis of 1-Naphthols // Organic Letters. 2017. Vol. 19. No. 23. pp. 6344-6347.
Cite this
RIS
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TY - JOUR
DO - 10.1021/acs.orglett.7b03186
UR - https://doi.org/10.1021/acs.orglett.7b03186
TI - Bromide-Mediated C–H Bond Functionalization: Intermolecular Annulation of Phenylethanone Derivatives with Alkynes for the Synthesis of 1-Naphthols
T2 - Organic Letters
AU - Lu, Tao
AU - Jiang, Ya Ting
AU - Ma, Feng Ping
AU - Tang, Zi Jing
AU - Liu, Kuang
AU - Wang, Yu-Xuan
AU - Wang, Bin
PY - 2017
DA - 2017/11/17
PB - American Chemical Society (ACS)
SP - 6344-6347
IS - 23
VL - 19
PMID - 29148795
SN - 1523-7060
SN - 1523-7052
ER -
Cite this
BibTex (up to 50 authors)
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@article{2017_Lu,
author = {Tao Lu and Ya Ting Jiang and Feng Ping Ma and Zi Jing Tang and Kuang Liu and Yu-Xuan Wang and Bin Wang},
title = {Bromide-Mediated C–H Bond Functionalization: Intermolecular Annulation of Phenylethanone Derivatives with Alkynes for the Synthesis of 1-Naphthols},
journal = {Organic Letters},
year = {2017},
volume = {19},
publisher = {American Chemical Society (ACS)},
month = {nov},
url = {https://doi.org/10.1021/acs.orglett.7b03186},
number = {23},
pages = {6344--6347},
doi = {10.1021/acs.orglett.7b03186}
}
Cite this
MLA
Copy
Lu, Tao, et al. “Bromide-Mediated C–H Bond Functionalization: Intermolecular Annulation of Phenylethanone Derivatives with Alkynes for the Synthesis of 1-Naphthols.” Organic Letters, vol. 19, no. 23, Nov. 2017, pp. 6344-6347. https://doi.org/10.1021/acs.orglett.7b03186.