volume 20 issue 24 pages 7947-7952

Expanding the Reactivity of Donor-Acceptor Cyclopropanes: Synthesis of Benzannulated Five-Membered Heterocycles via Intramolecular Attack of a Pendant Nucleophilic Group.

Publication typeJournal Article
Publication date2018-12-05
scimago Q1
wos Q1
SJR1.235
CiteScore8.7
Impact factor5.0
ISSN15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
Lewis-acid-induced domino transformations of donor-acceptor cyclopropanes, possessing a nucleophilic center embedded in a donor group, into functionalized 2,3-dihydrobenzo[ b]furans and 2,3-dihydrobenzo[ b]thiophenes are reported herein. An unusual switch of the electrophilic center in the three-membered ring, from the atom bearing a donor substituent to an unsubstituted carbon atom, was achieved by a judicious choice of Lewis acid, which induces the isomerization of a cyclopropane to an electrophilic alkene, and the length of linker, connecting a nucleophilic moiety and the small ring.
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Ivanova O. et al. Expanding the Reactivity of Donor-Acceptor Cyclopropanes: Synthesis of Benzannulated Five-Membered Heterocycles via Intramolecular Attack of a Pendant Nucleophilic Group. // Organic Letters. 2018. Vol. 20. No. 24. pp. 7947-7952.
GOST all authors (up to 50) Copy
Ivanova O., Andronov V. A., Vasin V. S., Shumsky A. N., Rybakov V. B., Voskressensky L. G., Trushkov I. V. Expanding the Reactivity of Donor-Acceptor Cyclopropanes: Synthesis of Benzannulated Five-Membered Heterocycles via Intramolecular Attack of a Pendant Nucleophilic Group. // Organic Letters. 2018. Vol. 20. No. 24. pp. 7947-7952.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/acs.orglett.8b03491
UR - https://doi.org/10.1021/acs.orglett.8b03491
TI - Expanding the Reactivity of Donor-Acceptor Cyclopropanes: Synthesis of Benzannulated Five-Membered Heterocycles via Intramolecular Attack of a Pendant Nucleophilic Group.
T2 - Organic Letters
AU - Ivanova, Olga
AU - Andronov, Vladimir A
AU - Vasin, Vladimir S
AU - Shumsky, Alexey N
AU - Rybakov, Victor B.
AU - Voskressensky, Leonid G.
AU - Trushkov, Igor V
PY - 2018
DA - 2018/12/05
PB - American Chemical Society (ACS)
SP - 7947-7952
IS - 24
VL - 20
PMID - 30517005
SN - 1523-7060
SN - 1523-7052
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2018_Ivanova,
author = {Olga Ivanova and Vladimir A Andronov and Vladimir S Vasin and Alexey N Shumsky and Victor B. Rybakov and Leonid G. Voskressensky and Igor V Trushkov},
title = {Expanding the Reactivity of Donor-Acceptor Cyclopropanes: Synthesis of Benzannulated Five-Membered Heterocycles via Intramolecular Attack of a Pendant Nucleophilic Group.},
journal = {Organic Letters},
year = {2018},
volume = {20},
publisher = {American Chemical Society (ACS)},
month = {dec},
url = {https://doi.org/10.1021/acs.orglett.8b03491},
number = {24},
pages = {7947--7952},
doi = {10.1021/acs.orglett.8b03491}
}
MLA
Cite this
MLA Copy
Ivanova, Olga, et al. “Expanding the Reactivity of Donor-Acceptor Cyclopropanes: Synthesis of Benzannulated Five-Membered Heterocycles via Intramolecular Attack of a Pendant Nucleophilic Group..” Organic Letters, vol. 20, no. 24, Dec. 2018, pp. 7947-7952. https://doi.org/10.1021/acs.orglett.8b03491.