volume 21 issue 5 pages 1379-1383

Stereoselective One-Pot Deconjugation, Aldol, and Stabilized Peterson Olefination of α-Trialkylsilyl-β-alkyl-α,β-Unsaturated Esters

Publication typeJournal Article
Publication date2019-02-20
scimago Q1
wos Q1
SJR1.235
CiteScore8.7
Impact factor5.0
ISSN15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A stereoselective reaction process including a one-pot deconjugation, aldol, and stabilized Peterson olefination of α-trialkylsilyl-β-alkyl-α,β-unsaturated esters coupled with aliphatic aldehydes is described. This sequential procedure afforded tri-and disubstituted conjugated diene ester products with dr values of 12-20:1 for the newly established alkene moieties in modest to good isolated yields.
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Probasco M. S., Johnson D. A., Jennings M. P. Stereoselective One-Pot Deconjugation, Aldol, and Stabilized Peterson Olefination of α-Trialkylsilyl-β-alkyl-α,β-Unsaturated Esters // Organic Letters. 2019. Vol. 21. No. 5. pp. 1379-1383.
GOST all authors (up to 50) Copy
Probasco M. S., Johnson D. A., Jennings M. P. Stereoselective One-Pot Deconjugation, Aldol, and Stabilized Peterson Olefination of α-Trialkylsilyl-β-alkyl-α,β-Unsaturated Esters // Organic Letters. 2019. Vol. 21. No. 5. pp. 1379-1383.
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RIS Copy
TY - JOUR
DO - 10.1021/acs.orglett.9b00069
UR - https://doi.org/10.1021/acs.orglett.9b00069
TI - Stereoselective One-Pot Deconjugation, Aldol, and Stabilized Peterson Olefination of α-Trialkylsilyl-β-alkyl-α,β-Unsaturated Esters
T2 - Organic Letters
AU - Probasco, Michael S
AU - Johnson, David A.
AU - Jennings, Michael P
PY - 2019
DA - 2019/02/20
PB - American Chemical Society (ACS)
SP - 1379-1383
IS - 5
VL - 21
PMID - 30785292
SN - 1523-7060
SN - 1523-7052
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{2019_Probasco,
author = {Michael S Probasco and David A. Johnson and Michael P Jennings},
title = {Stereoselective One-Pot Deconjugation, Aldol, and Stabilized Peterson Olefination of α-Trialkylsilyl-β-alkyl-α,β-Unsaturated Esters},
journal = {Organic Letters},
year = {2019},
volume = {21},
publisher = {American Chemical Society (ACS)},
month = {feb},
url = {https://doi.org/10.1021/acs.orglett.9b00069},
number = {5},
pages = {1379--1383},
doi = {10.1021/acs.orglett.9b00069}
}
MLA
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MLA Copy
Probasco, Michael S., et al. “Stereoselective One-Pot Deconjugation, Aldol, and Stabilized Peterson Olefination of α-Trialkylsilyl-β-alkyl-α,β-Unsaturated Esters.” Organic Letters, vol. 21, no. 5, Feb. 2019, pp. 1379-1383. https://doi.org/10.1021/acs.orglett.9b00069.