volume 21 issue 22 pages 9045-9049

Enantioselective Synthesis of Isoxazoline N-Oxides via Pd-Catalyzed Asymmetric Allylic Cycloaddition of Nitro-Containing Allylic Carbonates

Publication typeJournal Article
Publication date2019-11-07
scimago Q1
wos Q1
SJR1.235
CiteScore8.7
Impact factor5.0
ISSN15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A useful method for the enantioselective preparation of isoxazoline N-oxides via Pd-catalyzed asymmetric allylic cycloaddition of nitro-containing allylic carbonates has been developed. By using palladium complex in situ generated from Pd2(dba)3·CHCl3 and phosphoramidite L2 as a catalyst under mild conditions, the transformation afforded vinylated isoxazoline N-oxides in high yields with acceptably high enantioselectivities.
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GOST |
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GOST Copy
Zhao C. et al. Enantioselective Synthesis of Isoxazoline N-Oxides via Pd-Catalyzed Asymmetric Allylic Cycloaddition of Nitro-Containing Allylic Carbonates // Organic Letters. 2019. Vol. 21. No. 22. pp. 9045-9049.
GOST all authors (up to 50) Copy
Zhao C., Shah B. H., Khan I., Kan Y., Zhang Y. J. Enantioselective Synthesis of Isoxazoline N-Oxides via Pd-Catalyzed Asymmetric Allylic Cycloaddition of Nitro-Containing Allylic Carbonates // Organic Letters. 2019. Vol. 21. No. 22. pp. 9045-9049.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/acs.orglett.9b03443
UR - https://doi.org/10.1021/acs.orglett.9b03443
TI - Enantioselective Synthesis of Isoxazoline N-Oxides via Pd-Catalyzed Asymmetric Allylic Cycloaddition of Nitro-Containing Allylic Carbonates
T2 - Organic Letters
AU - Zhao, Can
AU - Shah, Babar Hussain
AU - Khan, Ijaz
AU - Kan, Yuhe
AU - Zhang, Yong Jian
PY - 2019
DA - 2019/11/07
PB - American Chemical Society (ACS)
SP - 9045-9049
IS - 22
VL - 21
PMID - 31697086
SN - 1523-7060
SN - 1523-7052
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2019_Zhao,
author = {Can Zhao and Babar Hussain Shah and Ijaz Khan and Yuhe Kan and Yong Jian Zhang},
title = {Enantioselective Synthesis of Isoxazoline N-Oxides via Pd-Catalyzed Asymmetric Allylic Cycloaddition of Nitro-Containing Allylic Carbonates},
journal = {Organic Letters},
year = {2019},
volume = {21},
publisher = {American Chemical Society (ACS)},
month = {nov},
url = {https://doi.org/10.1021/acs.orglett.9b03443},
number = {22},
pages = {9045--9049},
doi = {10.1021/acs.orglett.9b03443}
}
MLA
Cite this
MLA Copy
Zhao, Can, et al. “Enantioselective Synthesis of Isoxazoline N-Oxides via Pd-Catalyzed Asymmetric Allylic Cycloaddition of Nitro-Containing Allylic Carbonates.” Organic Letters, vol. 21, no. 22, Nov. 2019, pp. 9045-9049. https://doi.org/10.1021/acs.orglett.9b03443.