ACS applied materials & interfaces, volume 13, issue 8, pages 9500-9519
Recent Progress in Aptamer Discoveries and Modifications for Therapeutic Applications
Shuaijian Ni
1, 2, 3, 4
,
Zhen-Jian Zhuo
5
,
Yufei Pan
6
,
Yuanyuan Yu
1, 2, 3, 4
,
Fangfei Li
1, 2, 3, 4
,
Jin Liu
1, 2, 3, 4
,
Luyao Wang
1, 2, 3, 4
,
Xiaoqiu Wu
1, 2, 3, 4
,
Dijie Li
1, 2, 3, 4
,
Youyang Wan
1, 2, 3, 4
,
LIHE ZHANG
6
,
杨振军 Zhenjun Yang
6
,
Bao-Ting Zhang
5
,
Ai-ping Lu
1, 2, 3, 4
,
Ge Zhang
1, 2, 3, 4
1
Guangdong-Hong Kong-Macao Greater Bay Area International Research Platform for Aptamer-based Translational Medicine and Drug Discovery, Hong Kong 999077, China
|
Publication type: Journal Article
Publication date: 2020-06-30
Journal:
ACS applied materials & interfaces
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 9.5
ISSN: 19448244, 19448252
General Materials Science
Abstract
Aptamers are oligonucleotide sequences with a length of about 25-80 bases which have abilities to bind to specific target molecules that rival those of monoclonal antibodies. They are attracting great attention in diverse clinical translations on account of their various advantages, including prolonged storage life, little batch-to-batch differences, very low immunogenicity, and feasibility of chemical modifications for enhancing stability, prolonging the half-life in serum, and targeted delivery. In this Review, we demonstrate the emerging aptamer discovery technologies in developing advanced techniques for producing aptamers with high performance consistently and efficiently as well as requiring less cost and resources but offering a great chance of success. Further, the diverse modifications of aptamers for therapeutic applications including therapeutic agents, aptamer-drug conjugates, and targeted delivery materials are comprehensively summarized.
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Citations by publishers
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10
20
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40
50
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80
90
100
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Elsevier
99 publications, 31.43%
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IOP Publishing
1 publication, 0.32%
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PagePress
1 publication, 0.32%
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Thieme
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IEEE
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Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
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- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Ni S. et al. Recent Progress in Aptamer Discoveries and Modifications for Therapeutic Applications // ACS applied materials & interfaces. 2020. Vol. 13. No. 8. pp. 9500-9519.
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Ni S., Zhuo Z., Pan Y., Yu Y., Li F., Liu J., Wang L., Wu X., Li D., Wan Y., ZHANG L., Zhenjun Yang 杨., Zhang B., Lu A., Zhang G. Recent Progress in Aptamer Discoveries and Modifications for Therapeutic Applications // ACS applied materials & interfaces. 2020. Vol. 13. No. 8. pp. 9500-9519.
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TY - JOUR
DO - 10.1021/acsami.0c05750
UR - https://doi.org/10.1021/acsami.0c05750
TI - Recent Progress in Aptamer Discoveries and Modifications for Therapeutic Applications
T2 - ACS applied materials & interfaces
AU - Ni, Shuaijian
AU - Pan, Yufei
AU - Li, Fangfei
AU - Wang, Luyao
AU - Wu, Xiaoqiu
AU - Li, Dijie
AU - Wan, Youyang
AU - ZHANG, LIHE
AU - Zhang, Bao-Ting
AU - Zhenjun Yang, 杨振军
AU - Zhang, Ge
AU - Zhuo, Zhen-Jian
AU - Yu, Yuanyuan
AU - Liu, Jin
AU - Lu, Ai-ping
PY - 2020
DA - 2020/06/30 00:00:00
PB - American Chemical Society (ACS)
SP - 9500-9519
IS - 8
VL - 13
SN - 1944-8244
SN - 1944-8252
ER -
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@article{2020_Ni,
author = {Shuaijian Ni and Yufei Pan and Fangfei Li and Luyao Wang and Xiaoqiu Wu and Dijie Li and Youyang Wan and LIHE ZHANG and Bao-Ting Zhang and 杨振军 Zhenjun Yang and Ge Zhang and Zhen-Jian Zhuo and Yuanyuan Yu and Jin Liu and Ai-ping Lu},
title = {Recent Progress in Aptamer Discoveries and Modifications for Therapeutic Applications},
journal = {ACS applied materials & interfaces},
year = {2020},
volume = {13},
publisher = {American Chemical Society (ACS)},
month = {jun},
url = {https://doi.org/10.1021/acsami.0c05750},
number = {8},
pages = {9500--9519},
doi = {10.1021/acsami.0c05750}
}
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Ni, Shuaijian, et al. “Recent Progress in Aptamer Discoveries and Modifications for Therapeutic Applications.” ACS applied materials & interfaces, vol. 13, no. 8, Jun. 2020, pp. 9500-9519. https://doi.org/10.1021/acsami.0c05750.