Anisotropic Gold Nanoparticle Decorated Magnetopolymersome: An Advanced Nanocarrier for Targeted Photothermal Therapy and Dual-Mode Responsive T1 MRI Imaging
Publication type: Journal Article
Publication date: 2017-03-31
scimago Q1
wos Q2
SJR: 1.105
CiteScore: 9.7
Impact factor: 5.5
ISSN: 23739878
PubMed ID:
33440562
Biomaterials
Biomedical Engineering
Abstract
Herein, we report the advanced polymer vesicle [made up of triblock polymer: poly(ethylene oxide)-co-poly(Cys-AuNP@FA)-co-poly(3-methoxypropylacrylamide] having encapsulated magnetic nanoparticle capable of targeted methotrexate delivery (having folic acid as tagging agent), photothermal therapy [anisotropic gold nanoparticle (AuNPs)] and stimuli-responsive T1-imaging (as MRI contrast agent). The prepared polymersome, called as magnetopolymersome (MPS), after encapsulation of magnetic nanoparticle (Gd-doped) is not only high yield and simple in synthesis but also possess very high biocompatibility, more than 95% drug encapsulation efficiency and effective near-infrared (NIR) responsive photothermal therapy. The MPS is highly stable under normal physiological environments and other extreme end conditions (like presence of serum or Triton-X 100) and have excellent stimuli-responsive (temperature and NIR) T1-contrast effect in vitro conditions (60.57 mM–1 s–1). To explore the role of shape of AuNPs on the ph...
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13
Total citations:
13
Citations from 2024:
4
(33.33%)
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Roy E. et al. Anisotropic Gold Nanoparticle Decorated Magnetopolymersome: An Advanced Nanocarrier for Targeted Photothermal Therapy and Dual-Mode Responsive T1 MRI Imaging // ACS Biomaterials Science and Engineering. 2017. Vol. 3. No. 9. pp. 2120-2135.
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Roy E., Patra S., Madhuri R., Sharma P. Anisotropic Gold Nanoparticle Decorated Magnetopolymersome: An Advanced Nanocarrier for Targeted Photothermal Therapy and Dual-Mode Responsive T1 MRI Imaging // ACS Biomaterials Science and Engineering. 2017. Vol. 3. No. 9. pp. 2120-2135.
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RIS
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TY - JOUR
DO - 10.1021/acsbiomaterials.7b00089
UR - https://doi.org/10.1021/acsbiomaterials.7b00089
TI - Anisotropic Gold Nanoparticle Decorated Magnetopolymersome: An Advanced Nanocarrier for Targeted Photothermal Therapy and Dual-Mode Responsive T1 MRI Imaging
T2 - ACS Biomaterials Science and Engineering
AU - Roy, Ekta
AU - Patra, Santanu
AU - Madhuri, Rashmi
AU - Sharma, Prashant
PY - 2017
DA - 2017/03/31
PB - American Chemical Society (ACS)
SP - 2120-2135
IS - 9
VL - 3
PMID - 33440562
SN - 2373-9878
ER -
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BibTex (up to 50 authors)
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@article{2017_Roy,
author = {Ekta Roy and Santanu Patra and Rashmi Madhuri and Prashant Sharma},
title = {Anisotropic Gold Nanoparticle Decorated Magnetopolymersome: An Advanced Nanocarrier for Targeted Photothermal Therapy and Dual-Mode Responsive T1 MRI Imaging},
journal = {ACS Biomaterials Science and Engineering},
year = {2017},
volume = {3},
publisher = {American Chemical Society (ACS)},
month = {mar},
url = {https://doi.org/10.1021/acsbiomaterials.7b00089},
number = {9},
pages = {2120--2135},
doi = {10.1021/acsbiomaterials.7b00089}
}
Cite this
MLA
Copy
Roy, Ekta, et al. “Anisotropic Gold Nanoparticle Decorated Magnetopolymersome: An Advanced Nanocarrier for Targeted Photothermal Therapy and Dual-Mode Responsive T1 MRI Imaging.” ACS Biomaterials Science and Engineering, vol. 3, no. 9, Mar. 2017, pp. 2120-2135. https://doi.org/10.1021/acsbiomaterials.7b00089.