Open Access

ACS Omega

, volume 7 , issue 7 , pages 5864-5869

Functionalized Boron Nanoparticles as Potential Promising Antimalarial Agents

Yinghuai Zhu ¹

Parichat Prommana ²

Narayan S. Hosmane ³

Vincent Kam Wai Wong ⁴

Chairat Uthaipibull ²

Yingjun Zhang ¹

Hide authors affiliations Show authors affiliations: 4 affiliations

State Key Laboratory of Anti-Infective Drug Development (NO 2015DQ780357), Sunshine Lake Pharma Co., Ltd., Songshan Lake Industrial Park, Dongguan 523871, China |

National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), 113 Thailand Science Park, Pathum Thai 12120, Thailand

National Center for Genetic Engineering and Biotechnology

National Science and Technology Development Agency

Department of Chemistry and Biochemistry, Northern Illinois University, DeKalb, Illinois 60115, United States |

⁴

School Pharmacy, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau 999078, China |

Publication type: Journal Article

Publication date: 2022-02-09

American Chemical Society (ACS)

ACS Omega

scimago Q1

wos Q2

SJR: 0.773

CiteScore: 7.1

Impact factor: 4.3

ISSN: 24701343

DOI: 10.1021/acsomega.1c05888

Copy DOI

PubMed ID: 35224347

General Chemistry

General Chemical Engineering

Abstract

Boron nanoparticles (BNPs), functionalized with hydroxyl groups, were synthesized in situ by a cascade process, followed by bromination and hydrolyzation reactions. These functionalized BNPs, (Bm(OH)n), were characterized using 1H and 11B NMR spectra, Fourier-transform infrared (FT-IR) spectroscopy, inductively coupled plasma-optical emission spectroscopy (ICP-OES), transmission electron microscopy (TEM), dynamic light scattering (DLS), and X-ray photoelectron spectroscopy (XPS) methods. These nanoparticles were also evaluated in vitro for their antimalarial activity against Plasmodium falciparum (3D7 strain) with an IC50 value of 0.0021 μM and showed low toxicity to Uppsala 87 malignant glioma (U87MG) cell lines, malignant melanoma A375 cell lines, KB human oral cancer cell lines, rat cortical neuron cell lines, and rat fibroblast-like synoviocyte (FLS) cell lines.

Found

1 citation

Kubasov Alexey

🥼 🤝

PhD in Chemistry

116 publications, 1 149 citations, 43 reviews

h-index: 19

Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences

Research interests

Borides

Coordination Chemistry

Structural chemistry

Top-30

Journals

	1 2
ACS Applied Energy Materials	ACS Applied Energy Materials, 2, 10% ACS Applied Energy Materials 2 publications, 10%
Russian Journal of Inorganic Chemistry	Russian Journal of Inorganic Chemistry, 1, 5% Russian Journal of Inorganic Chemistry 1 publication, 5%
International Journal of Molecular Sciences	International Journal of Molecular Sciences, 1, 5% International Journal of Molecular Sciences 1 publication, 5%
Advanced Functional Materials	Advanced Functional Materials, 1, 5% Advanced Functional Materials 1 publication, 5%
FirePhysChem	FirePhysChem, 1, 5% FirePhysChem 1 publication, 5%
ACS Omega	ACS Omega, 1, 5% ACS Omega 1 publication, 5%
Defence Technology	Defence Technology, 1, 5% Defence Technology 1 publication, 5%
Brazilian Journal of Physics	Brazilian Journal of Physics, 1, 5% Brazilian Journal of Physics 1 publication, 5%
Applied Surface Science	Applied Surface Science, 1, 5% Applied Surface Science 1 publication, 5%
Toxicology Reports	Toxicology Reports, 1, 5% Toxicology Reports 1 publication, 5%
Physics of Particles and Nuclei Letters	Physics of Particles and Nuclei Letters, 1, 5% Physics of Particles and Nuclei Letters 1 publication, 5%
Mendeleev Communications	Mendeleev Communications, 1, 5% Mendeleev Communications 1 publication, 5%
Journal of Trace Elements in Medicine and Biology	Journal of Trace Elements in Medicine and Biology, 1, 5% Journal of Trace Elements in Medicine and Biology 1 publication, 5%
Nanoscale Advances	Nanoscale Advances, 1, 5% Nanoscale Advances 1 publication, 5%
Advanced Agrochem	Advanced Agrochem, 1, 5% Advanced Agrochem 1 publication, 5%
Results in Chemistry	Results in Chemistry, 1, 5% Results in Chemistry 1 publication, 5%
Materials Science and Engineering B: Solid-State Materials for Advanced Technology	Materials Science and Engineering B: Solid-State Materials for Advanced Technology, 1, 5% Materials Science and Engineering B: Solid-State Materials for Advanced Technology 1 publication, 5%
Research	Research, 1, 5% Research 1 publication, 5%
	1 2

Publishers

	1 2 3 4 5 6 7 8
Elsevier	Elsevier, 8, 40% Elsevier 8 publications, 40%
American Chemical Society (ACS)	American Chemical Society (ACS), 3, 15% American Chemical Society (ACS) 3 publications, 15%
Pleiades Publishing	Pleiades Publishing, 2, 10% Pleiades Publishing 2 publications, 10%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 2, 10% Royal Society of Chemistry (RSC) 2 publications, 10%
MDPI	MDPI, 1, 5% MDPI 1 publication, 5%
Wiley	Wiley, 1, 5% Wiley 1 publication, 5%
Springer Nature	Springer Nature, 1, 5% Springer Nature 1 publication, 5%
OOO Zhurnal "Mendeleevskie Soobshcheniya"	OOO Zhurnal "Mendeleevskie Soobshcheniya", 1, 5% OOO Zhurnal "Mendeleevskie Soobshcheniya" 1 publication, 5%
American Association for the Advancement of Science (AAAS)	American Association for the Advancement of Science (AAAS), 1, 5% American Association for the Advancement of Science (AAAS) 1 publication, 5%
	1 2 3 4 5 6 7 8

We do not take into account publications without a DOI.
Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.

PDF

Metrics

Cite this

GOST |

Cite this

GOST Copy

Zhu Y. et al. Functionalized Boron Nanoparticles as Potential Promising Antimalarial Agents // ACS Omega. 2022. Vol. 7. No. 7. pp. 5864-5869.

GOST all authors (up to 50) Copy

Zhu Y., Prommana P., Hosmane N. S., Wong V. K. W., Uthaipibull C., Zhang Y. Functionalized Boron Nanoparticles as Potential Promising Antimalarial Agents // ACS Omega. 2022. Vol. 7. No. 7. pp. 5864-5869.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1021/acsomega.1c05888

UR - https://doi.org/10.1021/acsomega.1c05888

TI - Functionalized Boron Nanoparticles as Potential Promising Antimalarial Agents

T2 - ACS Omega

AU - Zhu, Yinghuai

AU - Prommana, Parichat

AU - Hosmane, Narayan S.

AU - Wong, Vincent Kam Wai

AU - Uthaipibull, Chairat

AU - Zhang, Yingjun

PY - 2022

DA - 2022/02/09

PB - American Chemical Society (ACS)

SP - 5864-5869

IS - 7

VL - 7

PMID - 35224347

SN - 2470-1343

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2022_Zhu,

author = {Yinghuai Zhu and Parichat Prommana and Narayan S. Hosmane and Vincent Kam Wai Wong and Chairat Uthaipibull and Yingjun Zhang},

title = {Functionalized Boron Nanoparticles as Potential Promising Antimalarial Agents},

journal = {ACS Omega},

year = {2022},

volume = {7},

publisher = {American Chemical Society (ACS)},

month = {feb},

url = {https://doi.org/10.1021/acsomega.1c05888},

number = {7},

pages = {5864--5869},

doi = {10.1021/acsomega.1c05888}

}

MLA

Cite this

MLA Copy

Zhu, Yinghuai, et al. “Functionalized Boron Nanoparticles as Potential Promising Antimalarial Agents.” ACS Omega, vol. 7, no. 7, Feb. 2022, pp. 5864-5869. https://doi.org/10.1021/acsomega.1c05888.

Publisher

American Chemical Society (ACS)

Journal

ACS Omega

scimago Q1

wos Q2

SJR

0.773

CiteScore

7.1

Impact factor

4.3

ISSN

24701343 (Print, Electronic)