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volume 7 issue 16 pages 14345-14356

Oxidative Cyclization of 4-(2-Aminophenyl)-4-oxo-2-phenylbutanenitriles into 2-(3-Oxoindolin-2-ylidene)acetonitriles

Publication typeJournal Article
Publication date2022-04-15
scimago Q1
wos Q2
SJR0.773
CiteScore7.1
Impact factor4.3
ISSN24701343
General Chemistry
General Chemical Engineering
Abstract
A facile and highly efficient method for the preparation of 2-(3-oxoindolin-2-ylidene)acetonitriles from 4-(2-aminophenyl)-4-oxo-2-phenylbutanenitriles is described. The featured transformation operates via nucleophilic intramolecular cyclization and involves oxidation of the aniline moiety. Overall, this modification allowed for the improvement of yields and expansion of the reaction scope.
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Aksenov N. A. et al. Oxidative Cyclization of 4-(2-Aminophenyl)-4-oxo-2-phenylbutanenitriles into 2-(3-Oxoindolin-2-ylidene)acetonitriles // ACS Omega. 2022. Vol. 7. No. 16. pp. 14345-14356.
GOST all authors (up to 50) Copy
Aksenov N. A., Aksenov A., Prityko L. A., Aksenov D. A., Aksenova D. S., Nobi M. A., Rubin M. Oxidative Cyclization of 4-(2-Aminophenyl)-4-oxo-2-phenylbutanenitriles into 2-(3-Oxoindolin-2-ylidene)acetonitriles // ACS Omega. 2022. Vol. 7. No. 16. pp. 14345-14356.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1021/acsomega.2c01238
UR - https://doi.org/10.1021/acsomega.2c01238
TI - Oxidative Cyclization of 4-(2-Aminophenyl)-4-oxo-2-phenylbutanenitriles into 2-(3-Oxoindolin-2-ylidene)acetonitriles
T2 - ACS Omega
AU - Aksenov, Nicolai A
AU - Aksenov, Alexander V.
AU - Prityko, Lidiya A
AU - Aksenov, Dmitrii A
AU - Aksenova, Daria S
AU - Nobi, Mezvah A
AU - Rubin, Michael
PY - 2022
DA - 2022/04/15
PB - American Chemical Society (ACS)
SP - 14345-14356
IS - 16
VL - 7
PMID - 35573208
SN - 2470-1343
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2022_Aksenov,
author = {Nicolai A Aksenov and Alexander V. Aksenov and Lidiya A Prityko and Dmitrii A Aksenov and Daria S Aksenova and Mezvah A Nobi and Michael Rubin},
title = {Oxidative Cyclization of 4-(2-Aminophenyl)-4-oxo-2-phenylbutanenitriles into 2-(3-Oxoindolin-2-ylidene)acetonitriles},
journal = {ACS Omega},
year = {2022},
volume = {7},
publisher = {American Chemical Society (ACS)},
month = {apr},
url = {https://doi.org/10.1021/acsomega.2c01238},
number = {16},
pages = {14345--14356},
doi = {10.1021/acsomega.2c01238}
}
MLA
Cite this
MLA Copy
Aksenov, Nicolai A., et al. “Oxidative Cyclization of 4-(2-Aminophenyl)-4-oxo-2-phenylbutanenitriles into 2-(3-Oxoindolin-2-ylidene)acetonitriles.” ACS Omega, vol. 7, no. 16, Apr. 2022, pp. 14345-14356. https://doi.org/10.1021/acsomega.2c01238.