Open Access
Improved Solubility and Bioactivity of Camptothecin Family Antitumor Drugs with Supramolecular Encapsulation by Water-Soluble Pillar[6]arene
Publication type: Journal Article
Publication date: 2017-08-31
scimago Q1
wos Q2
SJR: 0.773
CiteScore: 7.1
Impact factor: 4.3
ISSN: 24701343
PubMed ID:
30023745
General Chemistry
General Chemical Engineering
Abstract
Water-soluble pillar[6]arene (WP6) was used to solubilize camptothecin family antitumor drugs. In the presence of WP6, the solubility of camptothecin (CPT) and 10-hydroxycamptothecin (HCPT) was enhanced by 380 and 40 times, respectively. The solubility enhancement is proved to be the result of the host-guest encapsulation by WP6. WP6 has a low cytotoxicity against normal MC 3T3-E1 cells, whereas the bioactivity of CPT and HCPT is substantially improved as a result of the solubility enhancement.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
|
|
|
Israel Journal of Chemistry
3 publications, 6.98%
|
|
|
Journal of Inclusion Phenomena and Macrocyclic Chemistry
2 publications, 4.65%
|
|
|
Colloids and Surfaces A: Physicochemical and Engineering Aspects
2 publications, 4.65%
|
|
|
International Journal of Pharmaceutics
2 publications, 4.65%
|
|
|
Bioorganic Chemistry
2 publications, 4.65%
|
|
|
Chemical Society Reviews
2 publications, 4.65%
|
|
|
Nanomedicine
1 publication, 2.33%
|
|
|
Aging
1 publication, 2.33%
|
|
|
Biosensors
1 publication, 2.33%
|
|
|
Science China Chemistry
1 publication, 2.33%
|
|
|
Food Science and Human Wellness
1 publication, 2.33%
|
|
|
Journal of Solution Chemistry
1 publication, 2.33%
|
|
|
Sensors and Actuators, A: Physical
1 publication, 2.33%
|
|
|
Journal of Pharmaceutical Sciences
1 publication, 2.33%
|
|
|
Journal of Luminescence
1 publication, 2.33%
|
|
|
Journal of Molecular Liquids
1 publication, 2.33%
|
|
|
Journal of Drug Delivery Science and Technology
1 publication, 2.33%
|
|
|
European Journal of Medicinal Chemistry
1 publication, 2.33%
|
|
|
Journal of Computational Chemistry
1 publication, 2.33%
|
|
|
Journal of Medicinal Chemistry
1 publication, 2.33%
|
|
|
ACS Omega
1 publication, 2.33%
|
|
|
ACS Applied Bio Materials
1 publication, 2.33%
|
|
|
ACS Applied Nano Materials
1 publication, 2.33%
|
|
|
Chemical Communications
1 publication, 2.33%
|
|
|
Organic and Biomolecular Chemistry
1 publication, 2.33%
|
|
|
International Journal of Nanomedicine
1 publication, 2.33%
|
|
|
Angewandte Chemie - International Edition
1 publication, 2.33%
|
|
|
Angewandte Chemie
1 publication, 2.33%
|
|
|
ChemistrySelect
1 publication, 2.33%
|
|
|
1
2
3
|
Publishers
|
2
4
6
8
10
12
14
|
|
|
Elsevier
13 publications, 30.23%
|
|
|
Wiley
7 publications, 16.28%
|
|
|
Springer Nature
5 publications, 11.63%
|
|
|
American Chemical Society (ACS)
4 publications, 9.3%
|
|
|
Royal Society of Chemistry (RSC)
4 publications, 9.3%
|
|
|
MDPI
3 publications, 6.98%
|
|
|
Taylor & Francis
2 publications, 4.65%
|
|
|
Impact Journals
1 publication, 2.33%
|
|
|
Tsinghua University Press
1 publication, 2.33%
|
|
|
Research Square Platform LLC
1 publication, 2.33%
|
|
|
OOO Zhurnal "Mendeleevskie Soobshcheniya"
1 publication, 2.33%
|
|
|
2
4
6
8
10
12
14
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
43
Total citations:
43
Citations from 2025:
4
(9.3%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Liu Y. et al. Improved Solubility and Bioactivity of Camptothecin Family Antitumor Drugs with Supramolecular Encapsulation by Water-Soluble Pillar[6]arene // ACS Omega. 2017. Vol. 2. No. 8. pp. 5283-5288.
GOST all authors (up to 50)
Copy
Liu Y., Chen X., Yu L., Ma D., Ding J. Improved Solubility and Bioactivity of Camptothecin Family Antitumor Drugs with Supramolecular Encapsulation by Water-Soluble Pillar[6]arene // ACS Omega. 2017. Vol. 2. No. 8. pp. 5283-5288.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/acsomega.7b01032
UR - https://doi.org/10.1021/acsomega.7b01032
TI - Improved Solubility and Bioactivity of Camptothecin Family Antitumor Drugs with Supramolecular Encapsulation by Water-Soluble Pillar[6]arene
T2 - ACS Omega
AU - Liu, Yamin
AU - Chen, Xi
AU - Yu, Lin
AU - Ma, Da
AU - Ding, Jiandong
PY - 2017
DA - 2017/08/31
PB - American Chemical Society (ACS)
SP - 5283-5288
IS - 8
VL - 2
PMID - 30023745
SN - 2470-1343
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2017_Liu,
author = {Yamin Liu and Xi Chen and Lin Yu and Da Ma and Jiandong Ding},
title = {Improved Solubility and Bioactivity of Camptothecin Family Antitumor Drugs with Supramolecular Encapsulation by Water-Soluble Pillar[6]arene},
journal = {ACS Omega},
year = {2017},
volume = {2},
publisher = {American Chemical Society (ACS)},
month = {aug},
url = {https://doi.org/10.1021/acsomega.7b01032},
number = {8},
pages = {5283--5288},
doi = {10.1021/acsomega.7b01032}
}
Cite this
MLA
Copy
Liu, Yamin, et al. “Improved Solubility and Bioactivity of Camptothecin Family Antitumor Drugs with Supramolecular Encapsulation by Water-Soluble Pillar[6]arene.” ACS Omega, vol. 2, no. 8, Aug. 2017, pp. 5283-5288. https://doi.org/10.1021/acsomega.7b01032.