Polymer-Stabilized Lanthanide Fluoride Nanoparticle Aggregates as Contrast Agents for Magnetic Resonance Imaging and Computed Tomography
Evelyn Ning Man Cheung
1
,
Rohan D A Alvares
2
,
Wendy K Oakden
3
,
Richa Chaudhary
2
,
Melissa L. Hill
3
,
Jothirmayanantham Pichaandi
4
,
Gary C H Mo
5
,
Christopher Yip
1
,
Paul MacDonald
2
,
Greg J. Stanisz
3
,
Yuanjian Zhang
4
,
R. Scott Prosser
1, 2
3
Publication type: Journal Article
Publication date: 2010-07-23
scimago Q1
wos Q1
SJR: 2.065
CiteScore: 12.0
Impact factor: 7.0
ISSN: 08974756, 15205002
Materials Chemistry
General Chemistry
General Chemical Engineering
Abstract
Poly(acrylic acid) consisting of 25 monomer units (PAA25) was used to stabilize nanoparticle aggregates (NPAs) consisting of either NaGdF4 or 50/50 mixtures of GdF3 and CeF3. The resulting polymer-stabilized nanoparticle aggregates (NPAs) were developed and tested for their application as contrast agents for magnetic resonance imaging (MRI) and computed tomography (CT). The PAA25-stabilized NPAs exhibit low polydispersity and are colloidally stable at concentrations of 40 mg/mL, while their sizes can be be controlled by choosing a specific ratio of Gd3+ to Ce3+. Scanning transmission electron microscopy (STEM) reveals that NaGdF4 NPAs possess an average diameter of 400 nm. High-resolution STEM and powder X-ray diffraction (XRD) both show that these NPAs consist of a stable aggregate of smaller NPs, whose diameters are 20−22 nm. PAA25-stabilized NPAs consisting of a 50/50 mixture of GdF3 and CeF3 possess an average diameter of 70 nm, while the fundamental unit size is estimated to be 10−12 nm in diameter. ...
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119
Total citations:
119
Citations from 2025:
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(3.36%)
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GOST
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Cheung E. N. M. et al. Polymer-Stabilized Lanthanide Fluoride Nanoparticle Aggregates as Contrast Agents for Magnetic Resonance Imaging and Computed Tomography // Chemistry of Materials. 2010. Vol. 22. No. 16. pp. 4728-4739.
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Cheung E. N. M., Alvares R. D. A., Oakden W. K., Chaudhary R., Hill M. L., Pichaandi J., Mo G. C. H., Yip C., MacDonald P., Stanisz G. J., Zhang Y., Prosser R. S. Polymer-Stabilized Lanthanide Fluoride Nanoparticle Aggregates as Contrast Agents for Magnetic Resonance Imaging and Computed Tomography // Chemistry of Materials. 2010. Vol. 22. No. 16. pp. 4728-4739.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/cm101036a
UR - https://doi.org/10.1021/cm101036a
TI - Polymer-Stabilized Lanthanide Fluoride Nanoparticle Aggregates as Contrast Agents for Magnetic Resonance Imaging and Computed Tomography
T2 - Chemistry of Materials
AU - Cheung, Evelyn Ning Man
AU - Alvares, Rohan D A
AU - Oakden, Wendy K
AU - Chaudhary, Richa
AU - Hill, Melissa L.
AU - Pichaandi, Jothirmayanantham
AU - Mo, Gary C H
AU - Yip, Christopher
AU - MacDonald, Paul
AU - Stanisz, Greg J.
AU - Zhang, Yuanjian
AU - Prosser, R. Scott
PY - 2010
DA - 2010/07/23
PB - American Chemical Society (ACS)
SP - 4728-4739
IS - 16
VL - 22
SN - 0897-4756
SN - 1520-5002
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2010_Cheung,
author = {Evelyn Ning Man Cheung and Rohan D A Alvares and Wendy K Oakden and Richa Chaudhary and Melissa L. Hill and Jothirmayanantham Pichaandi and Gary C H Mo and Christopher Yip and Paul MacDonald and Greg J. Stanisz and Yuanjian Zhang and R. Scott Prosser},
title = {Polymer-Stabilized Lanthanide Fluoride Nanoparticle Aggregates as Contrast Agents for Magnetic Resonance Imaging and Computed Tomography},
journal = {Chemistry of Materials},
year = {2010},
volume = {22},
publisher = {American Chemical Society (ACS)},
month = {jul},
url = {https://doi.org/10.1021/cm101036a},
number = {16},
pages = {4728--4739},
doi = {10.1021/cm101036a}
}
Cite this
MLA
Copy
Cheung, Evelyn Ning Man, et al. “Polymer-Stabilized Lanthanide Fluoride Nanoparticle Aggregates as Contrast Agents for Magnetic Resonance Imaging and Computed Tomography.” Chemistry of Materials, vol. 22, no. 16, Jul. 2010, pp. 4728-4739. https://doi.org/10.1021/cm101036a.