Solubility of Metoclopramide Hydrochloride in Six Green Solvents at (298.15 to 338.15) K
Publication type: Journal Article
Publication date: 2014-04-16
scimago Q2
wos Q2
SJR: 0.449
CiteScore: 4.0
Impact factor: 2.1
ISSN: 00219568, 15205134
General Chemistry
General Chemical Engineering
Abstract
In the present investigation, the solubility of metoclopramide hydrochloride (MHCl) in six green solvents, namely water, ethanol, propylene glycol (PG), polyethylene glycol-400 (PEG-400), ethylene glycol (EG), and Transcutol from (298.15 to 338.15) K was measured using an isothermal method. The measured solubilities of MHCl were correlated with the Apelblat equation at (298.15 to 338.15) K. The root-mean-square deviations (rmsd’s) were calculated with the help of experimental and calculated solubility data of MHCl. The rmsd’s were observed in the range of (0.063 to 0.569)·10–3 in all green solvents investigated. Moreover, the correlation coefficients in all green solvents were observed in the range of 0.993 to 0.998. The data of rmsd’s and correlation coefficients indicated good fitting of experimental data with calculated values. At 298.15 K (room temperature), the solubility of MHCl was found to be highest in EG (134.93·10–3 at 298.15 K) followed by water (51.61·10–3 at 298.15 K), Transcutol (48.17·10–3...
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Total citations:
13
Citations from 2024:
1
(7.69%)
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GOST
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Shakeel F. et al. Solubility of Metoclopramide Hydrochloride in Six Green Solvents at (298.15 to 338.15) K // Journal of Chemical & Engineering Data. 2014. Vol. 59. No. 5. pp. 1700-1703.
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Shakeel F., Shazly G. A., Haq N. Solubility of Metoclopramide Hydrochloride in Six Green Solvents at (298.15 to 338.15) K // Journal of Chemical & Engineering Data. 2014. Vol. 59. No. 5. pp. 1700-1703.
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RIS
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TY - JOUR
DO - 10.1021/je500154k
UR - https://doi.org/10.1021/je500154k
TI - Solubility of Metoclopramide Hydrochloride in Six Green Solvents at (298.15 to 338.15) K
T2 - Journal of Chemical & Engineering Data
AU - Shakeel, Faiyaz
AU - Shazly, Gamal A
AU - Haq, Nazrul
PY - 2014
DA - 2014/04/16
PB - American Chemical Society (ACS)
SP - 1700-1703
IS - 5
VL - 59
SN - 0021-9568
SN - 1520-5134
ER -
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BibTex (up to 50 authors)
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@article{2014_Shakeel,
author = {Faiyaz Shakeel and Gamal A Shazly and Nazrul Haq},
title = {Solubility of Metoclopramide Hydrochloride in Six Green Solvents at (298.15 to 338.15) K},
journal = {Journal of Chemical & Engineering Data},
year = {2014},
volume = {59},
publisher = {American Chemical Society (ACS)},
month = {apr},
url = {https://doi.org/10.1021/je500154k},
number = {5},
pages = {1700--1703},
doi = {10.1021/je500154k}
}
Cite this
MLA
Copy
Shakeel, Faiyaz, et al. “Solubility of Metoclopramide Hydrochloride in Six Green Solvents at (298.15 to 338.15) K.” Journal of Chemical & Engineering Data, vol. 59, no. 5, Apr. 2014, pp. 1700-1703. https://doi.org/10.1021/je500154k.