Novel Cyclopropapyrroloindole Derivative (AT-3510) Bearing Methoxycarbonyl and Trifluoromethyl Groups
Тип публикации: Journal Article
Дата публикации: 1999-04-02
scimago Q1
wos Q1
БС1
SJR: 1.801
CiteScore: 11.5
Impact factor: 6.8
ISSN: 00222623, 15204804
PubMed ID:
10212131
Drug Discovery
Molecular Medicine
Краткое описание
The seco-Cl 3-methoxycarbonyl-2-trifluoromethylcyclopropapyrroloindole (MCTFCPI) derivatives dl- and/or (S)-10 carrying various acyl moieties at the N6-position were synthesized along with their prodrugs (S)-12, and their antitumor activity was evaluated. Among these derivatives, AT-3510 [(S)-12m], the novel prodrug MCTFCPI derivative carrying a 5-(7-methoxybenzofuran-2-ylcarbonyl)aminoindole-2-carb onyl group at the N6-position, was found to exhibit more excellent antitumor activity against human tumor xenografts than the clinical trial candidates carzelesin (6) and KW-2189 (7) and cisplatin.
Найдено
Ничего не найдено, попробуйте изменить настройки фильтра.
Для доступа к списку цитирований публикации необходимо авторизоваться.
Топ-30
Журналы
|
1
2
3
4
5
6
|
|
|
Tetrahedron Letters
6 публикаций, 17.65%
|
|
|
Advanced Synthesis and Catalysis
4 публикации, 11.76%
|
|
|
Tetrahedron
3 публикации, 8.82%
|
|
|
Organic Letters
3 публикации, 8.82%
|
|
|
European Journal of Organic Chemistry
2 публикации, 5.88%
|
|
|
Synthesis
2 публикации, 5.88%
|
|
|
Journal of Medicinal Chemistry
1 публикация, 2.94%
|
|
|
American Journal of Clinical Oncology: Cancer Clinical Trials
1 публикация, 2.94%
|
|
|
Mendeleev Communications
1 публикация, 2.94%
|
|
|
Bioorganic and Medicinal Chemistry
1 публикация, 2.94%
|
|
|
Journal of Fluorine Chemistry
1 публикация, 2.94%
|
|
|
European Journal of Medicinal Chemistry
1 публикация, 2.94%
|
|
|
RSC Advances
1 публикация, 2.94%
|
|
|
Organic and Biomolecular Chemistry
1 публикация, 2.94%
|
|
|
Chemical Science
1 публикация, 2.94%
|
|
|
Expert Opinion on Therapeutic Patents
1 публикация, 2.94%
|
|
|
Topics in Heterocyclic Chemistry
1 публикация, 2.94%
|
|
|
Journal of Organic Chemistry
1 публикация, 2.94%
|
|
|
1
2
3
4
5
6
|
Издатели
|
2
4
6
8
10
12
|
|
|
Elsevier
12 публикаций, 35.29%
|
|
|
Wiley
6 публикаций, 17.65%
|
|
|
American Chemical Society (ACS)
5 публикаций, 14.71%
|
|
|
Royal Society of Chemistry (RSC)
3 публикации, 8.82%
|
|
|
Georg Thieme Verlag KG
2 публикации, 5.88%
|
|
|
Ovid Technologies (Wolters Kluwer Health)
1 публикация, 2.94%
|
|
|
OOO Zhurnal "Mendeleevskie Soobshcheniya"
1 публикация, 2.94%
|
|
|
Taylor & Francis
1 публикация, 2.94%
|
|
|
Springer Nature
1 публикация, 2.94%
|
|
|
2
4
6
8
10
12
|
- Мы не учитываем публикации, у которых нет DOI.
- Статистика публикаций обновляется еженедельно.
Вы ученый?
Создайте профиль, чтобы получать персональные рекомендации коллег, конференций и новых статей.
Метрики
34
Всего цитирований:
34
Цитирований c 2025:
2
(5.88%)
Цитировать
ГОСТ |
RIS |
BibTex |
MLA
Цитировать
ГОСТ
Скопировать
FUKUDA Y. et al. Novel Cyclopropapyrroloindole Derivative (AT-3510) Bearing Methoxycarbonyl and Trifluoromethyl Groups // Journal of Medicinal Chemistry. 1999. Vol. 42. No. 8. pp. 1448-1458.
ГОСТ со всеми авторами (до 50)
Скопировать
FUKUDA Y., Furuta H., Kusama Y., Ebisu H., OOMORI Y., Terashima S. Novel Cyclopropapyrroloindole Derivative (AT-3510) Bearing Methoxycarbonyl and Trifluoromethyl Groups // Journal of Medicinal Chemistry. 1999. Vol. 42. No. 8. pp. 1448-1458.
Цитировать
RIS
Скопировать
TY - JOUR
DO - 10.1021/jm980668c
UR - https://pubs.acs.org/doi/10.1021/jm980668c
TI - Novel Cyclopropapyrroloindole Derivative (AT-3510) Bearing Methoxycarbonyl and Trifluoromethyl Groups
T2 - Journal of Medicinal Chemistry
AU - FUKUDA, Yasumichi
AU - Furuta, Hirosuke
AU - Kusama, Yoshie
AU - Ebisu, Hiroyuki
AU - OOMORI, Yasuo
AU - Terashima, Shiro
PY - 1999
DA - 1999/04/02
PB - American Chemical Society (ACS)
SP - 1448-1458
IS - 8
VL - 42
PMID - 10212131
SN - 0022-2623
SN - 1520-4804
ER -
Цитировать
BibTex (до 50 авторов)
Скопировать
@article{1999_FUKUDA,
author = {Yasumichi FUKUDA and Hirosuke Furuta and Yoshie Kusama and Hiroyuki Ebisu and Yasuo OOMORI and Shiro Terashima},
title = {Novel Cyclopropapyrroloindole Derivative (AT-3510) Bearing Methoxycarbonyl and Trifluoromethyl Groups},
journal = {Journal of Medicinal Chemistry},
year = {1999},
volume = {42},
publisher = {American Chemical Society (ACS)},
month = {apr},
url = {https://pubs.acs.org/doi/10.1021/jm980668c},
number = {8},
pages = {1448--1458},
doi = {10.1021/jm980668c}
}
Цитировать
MLA
Скопировать
FUKUDA, Yasumichi, et al. “Novel Cyclopropapyrroloindole Derivative (AT-3510) Bearing Methoxycarbonyl and Trifluoromethyl Groups.” Journal of Medicinal Chemistry, vol. 42, no. 8, Apr. 1999, pp. 1448-1458. https://pubs.acs.org/doi/10.1021/jm980668c.