First Enantioselective Total Synthesis of (8S,12R,15S)-Prostaglandin J2
Publication type: Journal Article
Publication date: 2003-07-03
scimago Q2
wos Q1
SJR: 0.737
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
PubMed ID:
12895084
Organic Chemistry
Abstract
Enantioselective synthesis of natural PGJ(2) has been accomplished for the first time starting from the commercially available enantiopure aldehyde 7 in 10% overall yield. The key reaction was a novel prostaglandin class interconversion, i.e., an allylic 1,3-transposition across alcohol 9 derived from compound 14 in 73% overall yield. In principle, the unnatural enantiomer of PGJ(2) could be obtained starting from the commercially available enantiopure monobenzoate 7a following our strategy.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
|
|
|
Chemical Communications
3 publications, 14.29%
|
|
|
Organic Letters
2 publications, 9.52%
|
|
|
Chemical Reviews
2 publications, 9.52%
|
|
|
Russian Journal of Organic Chemistry
2 publications, 9.52%
|
|
|
Synlett
1 publication, 4.76%
|
|
|
Prostaglandins and Other Lipid Mediators
1 publication, 4.76%
|
|
|
Pathologie Biologie
1 publication, 4.76%
|
|
|
Tetrahedron Letters
1 publication, 4.76%
|
|
|
Tetrahedron
1 publication, 4.76%
|
|
|
ChemInform
1 publication, 4.76%
|
|
|
ChemistrySelect
1 publication, 4.76%
|
|
|
Organic and Biomolecular Chemistry
1 publication, 4.76%
|
|
|
RSC Advances
1 publication, 4.76%
|
|
|
Organic Preparations and Procedures International
1 publication, 4.76%
|
|
|
Journal of Pharmacy and Pharmacology
1 publication, 4.76%
|
|
|
Mendeleev Communications
1 publication, 4.76%
|
|
|
1
2
3
|
Publishers
|
1
2
3
4
5
|
|
|
Elsevier
5 publications, 23.81%
|
|
|
Royal Society of Chemistry (RSC)
5 publications, 23.81%
|
|
|
American Chemical Society (ACS)
4 publications, 19.05%
|
|
|
Wiley
3 publications, 14.29%
|
|
|
Pleiades Publishing
2 publications, 9.52%
|
|
|
Georg Thieme Verlag KG
1 publication, 4.76%
|
|
|
Taylor & Francis
1 publication, 4.76%
|
|
|
1
2
3
4
5
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
21
Total citations:
21
Citations from 2025:
0
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Zanoni G. et al. First Enantioselective Total Synthesis of (8S,12R,15S)-Prostaglandin J2 // Journal of Organic Chemistry. 2003. Vol. 68. No. 16. pp. 6437-6439.
GOST all authors (up to 50)
Copy
Zanoni G., Porta A., De Toma Q., Castronovo F., Vidari G. First Enantioselective Total Synthesis of (8S,12R,15S)-Prostaglandin J2 // Journal of Organic Chemistry. 2003. Vol. 68. No. 16. pp. 6437-6439.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/jo034502h
UR - https://doi.org/10.1021/jo034502h
TI - First Enantioselective Total Synthesis of (8S,12R,15S)-Prostaglandin J2
T2 - Journal of Organic Chemistry
AU - Zanoni, Giuseppe
AU - Porta, Alessio
AU - De Toma, Quintino
AU - Castronovo, Francesca
AU - Vidari, G.
PY - 2003
DA - 2003/07/03
PB - American Chemical Society (ACS)
SP - 6437-6439
IS - 16
VL - 68
PMID - 12895084
SN - 0022-3263
SN - 1520-6904
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2003_Zanoni,
author = {Giuseppe Zanoni and Alessio Porta and Quintino De Toma and Francesca Castronovo and G. Vidari},
title = {First Enantioselective Total Synthesis of (8S,12R,15S)-Prostaglandin J2},
journal = {Journal of Organic Chemistry},
year = {2003},
volume = {68},
publisher = {American Chemical Society (ACS)},
month = {jul},
url = {https://doi.org/10.1021/jo034502h},
number = {16},
pages = {6437--6439},
doi = {10.1021/jo034502h}
}
Cite this
MLA
Copy
Zanoni, Giuseppe, et al. “First Enantioselective Total Synthesis of (8S,12R,15S)-Prostaglandin J2.” Journal of Organic Chemistry, vol. 68, no. 16, Jul. 2003, pp. 6437-6439. https://doi.org/10.1021/jo034502h.